Rifampin and Topamax drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Rifampin (rifampin) and Topamax (topiramate). Common drug interactions include dermatitis among females and abdominal pain among males.

The phase IV clinical study analyzes what interactions people have when they take Rifampin and Topamax. It is created by eHealthMe based on reports of 29 people who take the same drugs from the FDA, and is updated regularly.

What is Rifampin?

Rifampin has active ingredients of rifampin. It is often used in tuberculosis. eHealthMe is studying from 12,339 Rifampin users. Check the latest studies of Rifampin.

What is Topamax?

Topamax has active ingredients of topiramate. It is often used in migraine. eHealthMe is studying from 58,954 Topamax users. Check the latest studies of Topamax.

On Jul, 06, 2026

29 people who take Rifampin and Topamax together, and have interactions are studied.

What are the common drug interactions of Rifampin and Topamax, by gender? *:

female:

Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
Diabetes mellitus inadequate control
Diabetic gastropathy (gastric neuromuscular dysfunction in diabetes mellitus)
Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
Diarrhoea
Disability
Disease recurrence
Disturbance in attention
Drug dependence

male:

Abdominal pain
Cardiac disorder
Pain
Pain in extremity
Procedural site reaction
Pulmonary embolism (blockage of the main artery of the lung)
Pulmonary hypertension (increase in blood pressure in the lung artery)
Subcutaneous abscess
Subcutaneous haematoma (collection of blood outside the blood vessels on the skin)
Thrombophlebitis superficial (swelling (inflammation) of a superficial vein caused by a blood clot)

What are the common drug interactions of Rifampin and Topamax, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Papillary thyroid cancer
Suicidal ideation
Autoimmune thyroiditis (form of thyroiditis associated with an autoimmune disease)

30-39:

Abdominal discomfort
Abdominal pain
Anxiety
Dizziness
Dyspnoea (difficult or laboured respiration)
Hypotension (abnormally low blood pressure)
Memory impairment
Suicidal ideation

40-49:

Chronic kidney disease
Nasal obstruction (blockage of nose)
Pneumonia
Renal failure (kidney dysfunction)

50-59:

Contusion (a type of hematoma of tissue in which capillaries)
Dyspepsia (indigestion)
Renal failure (kidney dysfunction)
Renal injury (kidney injury)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
Disease recurrence
Limb injury
Renal failure acute (rapid kidney dysfunction)
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
Road traffic accident

60+:

Drug hypersensitivity

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 16 people, 55.17%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 6 people, 20.69%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 13.79%
High Blood Pressure: 3 people, 10.34%
High Blood Cholesterol: 3 people, 10.34%
Type 2 Diabetes: 2 people, 6.90%
Stress And Anxiety: 2 people, 6.90%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 2 people, 6.90%
Pain: 2 people, 6.90%
Oedema (fluid collection in tissue): 2 people, 6.90%

* Approximation only. Some reports may have incomplete information.

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