Olux and Methotrexate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Olux (clobetasol propionate) and Methotrexate (methotrexate sodium). Common drug interactions include psoriasis among females and arthralgia among males.

The phase IV clinical study analyzes what interactions people have when they take Olux and Methotrexate. It is created by eHealthMe based on reports of 44 people who take the same drugs from the FDA, and is updated regularly.

What is Olux?

Olux has active ingredients of clobetasol propionate. eHealthMe is studying from 614 Olux users. Check the latest studies of Olux.

What is Methotrexate?

Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. eHealthMe is studying from 604,312 Methotrexate users. Check the latest studies of Methotrexate.

On Jul, 13, 2026

44 people who take Olux and Methotrexate together, and have interactions are studied.

Olux and Methotrexate drug interactions.

What are the common drug interactions of Olux and Methotrexate, by gender? *:

female:

Psoriasis (immune-mediated disease that affects the skin)
Drug ineffective
Fatigue (feeling of tiredness)
Hot flush (sudden feelings of heat)
Skin plaque (red, scaly patches to appear on the skin)
Anxiety
Arthralgia (joint pain)
Depression
Dysphagia (a condition in which swallowing is difficult or painful)
Endometrial cancer recurrent

male:

Arthralgia (joint pain)
Psoriasis (immune-mediated disease that affects the skin)
Pain in extremity
Peripheral swelling
Rash
Rash erythematous (redness of the skin)
Rash macular (small, flat red spots)
Skin discolouration (change of skin colour)
Skin exfoliation (removal of the oldest dead skin cells)
Skin hyperpigmentation (disorders affect the colour of your skin)

What are the common drug interactions of Olux and Methotrexate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Diabetes mellitus inadequate control
Gait disturbance
Muscular weakness (muscle weakness)
Narcissistic personality disorder (a personality disorder in which the individual is described as being excessively preoccupied with issues of personal)
Pain
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Psoriasis (immune-mediated disease that affects the skin)
Scab (a hard coating on the skin formed during the wound healing)
Schizoaffective disorder (a mental disorder characterized by disordered thought)
Skin disorder (skin disease)

40-49:

Injection site pain
Migraine (headache)

50-59:

Endometrial cancer recurrent
Endometrial cancer
Endometrial cancer metastatic
Arthralgia (joint pain)
B-cell lymphoma (blood cancer affecting b cells)
Hot flush (sudden feelings of heat)

60+:

Arthralgia (joint pain)
Atrioventricular block first degree (heart block first degree)
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
Fatigue (feeling of tiredness)
Gait disturbance
Joint swelling
Pain
Psoriasis (immune-mediated disease that affects the skin)
Supraventricular tachycardia (rapid heart rhythm originating at or above the atrioventricular node)
Weight increased

What are the existing conditions these people have? *

Psoriasis (immune-mediated disease that affects the skin): 32 people, 72.73%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 15 people, 34.09%
High Blood Pressure: 10 people, 22.73%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 7 people, 15.91%
Type 2 Diabetes: 3 people, 6.82%
Diabetes: 3 people, 6.82%

* Approximation only. Some reports may have incomplete information.

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