Omeprazole and Evamist drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Omeprazole (omeprazole) and Evamist (estradiol). Common drug interactions include headache among females.

The phase IV clinical study analyzes what interactions people have when they take Omeprazole and Evamist. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Omeprazole?

Omeprazole has active ingredients of omeprazole. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 410,631 Omeprazole users. Check the latest studies of Omeprazole.

What is Evamist?

Evamist has active ingredients of estradiol. It is often used in hormone replacement therapy. eHealthMe is studying from 671 Evamist users. Check the latest studies of Evamist.



On Jul, 19, 2026

22 people who take Omeprazole and Evamist together, and have interactions are studied.

Omeprazole and Evamist drug interactions.

What are the common drug interactions of Omeprazole and Evamist, by gender? *:

female:

  1. Headache (pain in head)
  2. Poor quality sleep
  3. Application site urticaria
  4. Application site vesicles (small bubble within a cell at application site)
  5. Arthralgia (joint pain)
  6. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  7. Back injury
  8. Back pain
  9. Bone density decreased
  10. Bone loss

male:

n/a

What are the common drug interactions of Omeprazole and Evamist, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Chronic kidney disease
  2. Cough
  3. Nasopharyngitis (inflammation of the nasopharynx)
  4. Oropharyngeal pain

50-59:

  1. Back pain
  2. Drug effect decreased
  3. Headache (pain in head)
  4. Hypersensitivity
  5. Initial insomnia (feeling of inadequate or poor-quality sleep)
  6. Oropharyngeal pain
  7. Skin discolouration (change of skin colour)
  8. Skin hyperpigmentation (disorders affect the colour of your skin)
  9. Skin hypopigmentation (loss of skin colour)
  10. Skin irritation

60+:

  1. Application site erythema (redness of the skin at application site)
  2. Application site pruritus (application site severe itching of the skin)
  3. Emotional distress
  4. Fracture
  5. Fractured coccyx (fracture tail bone)
  6. Lumbar radiculopathy (radicular pain in the low back and legs)
  7. Mass
  8. Osteopenia (a condition where bone mineral density is lower than normal)
  9. Osteoporosis (bones weak and more likely to break)
  10. Post laminectomy syndrome

What are the existing conditions these people have? *

  1. Stress And Anxiety: 6 people, 27.27%
  2. Pain: 6 people, 27.27%
  3. Nausea (feeling of having an urge to vomit): 5 people, 22.73%
  4. Migraine (headache): 5 people, 22.73%
  5. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 5 people, 22.73%
  6. High Blood Cholesterol: 5 people, 22.73%
  7. Insomnia (sleeplessness): 5 people, 22.73%
  8. High Blood Pressure: 4 people, 18.18%
  9. Cough: 4 people, 18.18%
  10. Gastric Ulcer (stomach ulcer): 4 people, 18.18%

* Approximation only. Some reports may have incomplete information.

Do you take Omeprazole and Evamist?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Omeprazole and Evamist:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Omeprazole:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Evamist:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Omeprazole and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Evamist and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on omeprazole and estradiol (the active ingredients of Omeprazole and Evamist, respectively), and Omeprazole and Evamist (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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