Omeprazole and Nac drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Omeprazole (omeprazole) and Nac (n - acetyl cysteine). Common drug interactions include productive cough among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Omeprazole and Nac. It is created by eHealthMe based on reports of 51 people who take the same drugs from the FDA, and is updated regularly.

What is Omeprazole?

Omeprazole has active ingredients of omeprazole. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 410,631 Omeprazole users. Check the latest studies of Omeprazole.

What is Nac?

Nac has active ingredients of n - acetyl cysteine. eHealthMe is studying from 858 Nac users. Check the latest studies of Nac.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

51 people who take Omeprazole and Nac together, and have interactions are studied.

What are the common drug interactions of Omeprazole and Nac, by gender? *:

female:

Productive cough
Tooth infection
Anxiety
Back pain
Blood creatinine increased
Blood glucose increased
Blood uric acid increased
Depression
Device related infection
Dyspnoea (difficult or laboured respiration)

male:

Diarrhoea
Decreased appetite
Rhinorrhoea (watery mucus discharge from the nose)
Weight decreased
Vomiting
Fall
Influenza like illness
Insomnia (sleeplessness)
Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
Urinary tract infection enterococcal

What are the common drug interactions of Omeprazole and Nac, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Adverse event

20-29:

Anxiety
Depression
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Obsessive-compulsive disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;)
Stress
Mood altered (changes in mood)
Adverse drug reaction

30-39:

n/a

40-49:

n/a

50-59:

Nightmare (unpleasant dream)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Peripheral swelling
Platelet count increased
Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
Skin discolouration (change of skin colour)
Skin disorder (skin disease)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Urine abnormality
Vitreous floaters (spots before the eyes)

60+:

Fatigue (feeling of tiredness)
Nausea (feeling of having an urge to vomit)
Back pain
Dizziness
Hypertension (high blood pressure)
Nasopharyngitis (inflammation of the nasopharynx)
Pain
Rhinorrhoea (watery mucus discharge from the nose)
Vomiting
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)

What are the existing conditions these people have? *

Immunodeficiency Common Variable: 8 people, 15.69%
Idiopathic Pulmonary Fibrosis (chronic lung disease): 6 people, 11.76%
Multiple Myeloma (cancer of the plasma cells): 4 people, 7.84%
Insomnia (sleeplessness): 4 people, 7.84%
Pain: 3 people, 5.88%
Orthostatic Hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up): 3 people, 5.88%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 5.88%
Cystic Fibrosis (disease of the secretary glands): 3 people, 5.88%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 3 people, 5.88%
Constipation: 3 people, 5.88%

* Approximation only. Some reports may have incomplete information.

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