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Omeprazole and Picato drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Omeprazole (omeprazole) and Picato (ingenol mebutate). Common drug interactions include application site vesicles among females and application site erythema among males.

The phase IV clinical study analyzes what interactions people have when they take Omeprazole and Picato. It is created by eHealthMe based on reports of 48 people who take the same drugs from the FDA, and is updated regularly.

What is Omeprazole?

Omeprazole has active ingredients of omeprazole. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 410,631 Omeprazole users. Check the latest studies of Omeprazole.

What is Picato?

Picato has active ingredients of ingenol mebutate. eHealthMe is studying from 5,498 Picato users. Check the latest studies of Picato.

On Jul, 21, 2026

48 people who take Omeprazole and Picato together, and have interactions are studied.

Omeprazole and Picato drug interactions.

What are the common drug interactions of Omeprazole and Picato, by gender? *:

female:

  1. Application site vesicles (small bubble within a cell at application site)
  2. Application site pain
  3. Application site erythema (redness of the skin at application site)
  4. Application site discharge
  5. Application site irritation
  6. Application site exfoliation (application site removal of the oldest dead skin cells on the skin's outermost surface)
  7. Application site infection
  8. Arthralgia (joint pain)
  9. Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
  10. Erythema (redness of the skin)

male:

  1. Application site erythema (redness of the skin at application site)
  2. Application site pain
  3. Application site swelling
  4. Balance disorder
  5. Dysarthria (speech disorder)
  6. Hypoaesthesia (reduced sense of touch or sensation)
  7. Pain
  8. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  9. Aphasia (damage to the parts of the brain that control language)
  10. Application site discolouration

What are the common drug interactions of Omeprazole and Picato, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Application site erythema (redness of the skin at application site)
  2. Application site pain
  3. Application site erosion
  4. Application site pustules (small bumps on the skin that fill with fluid or pus at application site)
  5. Application site swelling
  6. Application site vesicles (small bubble within a cell at application site)
  7. Headache (pain in head)
  8. Pain
  9. Periorbital oedema (swelling around the eyes)
  10. Rash generalised (rash on most of body parts)

50-59:

  1. Suicidal ideation
  2. Application site erythema (redness of the skin at application site)
  3. Application site vesicles (small bubble within a cell at application site)
  4. Application site exfoliation (application site removal of the oldest dead skin cells on the skin's outermost surface)
  5. Application site fissure (ulcer at application site)
  6. Application site pain
  7. Application site scab (hard coating on the skin formed at application site)
  8. Application site swelling
  9. Application site ulcer
  10. Feeling hot

60+:

  1. Application site vesicles (small bubble within a cell at application site)
  2. Application site pain
  3. Application site reaction
  4. Application site scar
  5. Arthralgia (joint pain)
  6. Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
  7. Erythema (redness of the skin)
  8. Eye swelling
  9. Joint instability (a condition in which the joints aren't sufficiently supported)
  10. Swelling face

What are the existing conditions these people have? *

  1. Actinic Keratosis (skin disease due to sun exposure): 21 people, 43.75%
  2. High Blood Pressure: 4 people, 8.33%
  3. High Blood Cholesterol: 4 people, 8.33%
  4. Skin Cancer: 3 people, 6.25%
  5. Precancerous Skin Lesion: 3 people, 6.25%
  6. Dyslipidaemia (abnormal amount of lipids): 3 people, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Omeprazole and Picato?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Omeprazole and Picato:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Omeprazole:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Picato:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Omeprazole and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Picato and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on omeprazole and ingenol mebutate (the active ingredients of Omeprazole and Picato, respectively), and Omeprazole and Picato (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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