Omeprazole and Thioctic acid drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Omeprazole (omeprazole) and Thioctic acid (alpha - lipoic acid). Common drug interactions include extremity necrosis among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Omeprazole and Thioctic acid. It is created by eHealthMe based on reports of 46 people who take the same drugs from the FDA, and is updated regularly.

What is Omeprazole?

Omeprazole has active ingredients of omeprazole. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 410,631 Omeprazole users. Check the latest studies of Omeprazole.

What is Thioctic acid?

Thioctic acid has active ingredients of alpha - lipoic acid. eHealthMe is studying from 536 Thioctic acid users. Check the latest studies of Thioctic acid.

On Jul, 17, 2026

46 people who take Omeprazole and Thioctic acid together, and have interactions are studied.

Omeprazole and Thioctic acid drug interactions.

What are the common drug interactions of Omeprazole and Thioctic Acid, by gender? *:

female:

Extremity necrosis (death of body tissue of arms and legs)
Fall
Fear
Femur fracture
Foot fracture
Graft versus host disease in skin (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the skin)
Haemorrhoids (a swollen vein or group of veins in the region of the anus)
Headache (pain in head)
Hearing impaired
Heart rate decreased

male:

Diarrhoea
Anaemia (lack of blood)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Chemotherapy
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Depression
Diabetes mellitus inadequate control
Drug ineffective
Fatigue (feeling of tiredness)
General physical health deterioration (weak health status)

What are the common drug interactions of Omeprazole and Thioctic Acid, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Fatigue (feeling of tiredness)
Fear
Gait disturbance
Hypoaesthesia (reduced sense of touch or sensation)
Influenza
Injury
Joint stiffness

30-39:

Insomnia (sleeplessness)
Nausea (feeling of having an urge to vomit)
Therapeutic response unexpected

40-49:

Blood chromogranin a increased
Chronic kidney disease
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
Diabetes mellitus inadequate control

50-59:

Adverse event
Central venous pressure decreased
Chemotherapy
Fatigue (feeling of tiredness)
Hypersensitivity
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
Overdose
Polyuria (production of too much dilute urine)
Renal salt-wasting syndrome (lack of sodium due to excess excretion in urine)

60+:

Chronic kidney disease
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Gastroenteritis (inflammation of stomach and intestine)
Troponin i increased
Dyspnoea (difficult or laboured respiration)
Extrasystoles
Insomnia (sleeplessness)
Muscle spasms (muscle contraction)
Neuropathy peripheral (surface nerve damage)
Alanine aminotransferase increased

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 18 people, 39.13%
High Blood Pressure: 8 people, 17.39%
Pain: 4 people, 8.70%
Renal Disorder (kidney disease): 3 people, 6.52%
Joint Pain: 3 people, 6.52%

* Approximation only. Some reports may have incomplete information.

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