Omnicef and Oxycodone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Omnicef (cefdinir) and Oxycodone (oxycodone hydrochloride). Common drug interactions include compression fracture among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Omnicef and Oxycodone. It is created by eHealthMe based on reports of 61 people who take the same drugs from the FDA, and is updated regularly.

What is Omnicef?

Omnicef has active ingredients of cefdinir. It is often used in sinusitis. eHealthMe is studying from 2,774 Omnicef users. Check the latest studies of Omnicef.

What is Oxycodone?

Oxycodone has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 162,592 Oxycodone users. Check the latest studies of Oxycodone.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 21, 2026

61 people who take Omnicef and Oxycodone together, and have interactions are studied.

Omnicef and Oxycodone drug interactions.

What are the common drug interactions of Omnicef and Oxycodone, by gender? *:

female:

Compression fracture (fracture due to pressure caused by injury)
Dysarthria (speech disorder)
Exostosis (formation of new bone on the surface of a bone)
Spondylolysis (a defect of a vertebra)
Synovial cyst (cyst of joint filled with synovial fluid)
Tendon injury
Angina pectoris (chest pain due to ischemia of the heart muscle)
Atelectasis (partial or complete collapse of the lung)
Comminuted fracture (bone has broken into several pieces)
Renal cyst (kidney cyst)

male:

Chronic kidney disease
Renal failure (kidney dysfunction)
Bacterial sepsis
Cardiac arrest
Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Dependence on respirator
Diarrhoea
Gastric cancer stage iv (cancer cells have spread to distant organs)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
General symptom

What are the common drug interactions of Omnicef and Oxycodone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Chest pain
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Non-cardiac chest pain
Pleural effusion (water on the lungs)
Pulmonary embolism (blockage of the main artery of the lung)
Dyspnoea (difficult or laboured respiration)
Haematemesis (vomiting of blood)
Pulmonary fibrosis (formation or development of excess fibrous connective tissue (fibrosis) in the lungs)
Scar
Abdominal pain

20-29:

Adenomyosis (presence of ectopic glandular tissue found in muscle)
Adnexa uteri mass (ovarian cysts)
Amenorrhoea (absence of a menstrual period in a woman of reproductive age)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Arthralgia (joint pain)
Bone erosion
Bone swelling
Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
Cellulitis (infection under the skin)

30-39:

Chronic kidney disease
Renal failure (kidney dysfunction)
Nephrogenic anaemia (anaemia due to kidney disease)
Nausea (feeling of having an urge to vomit)

40-49:

Chronic kidney disease
Renal failure (kidney dysfunction)
Emotional disorder
Fatigue (feeling of tiredness)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nausea (feeling of having an urge to vomit)
Nephrogenic anaemia (anaemia due to kidney disease)
Pain in extremity
Rash
Renal injury (kidney injury)

50-59:

Headache (pain in head)
Muscle spasms (muscle contraction)
Upper respiratory tract infection
Abdominal discomfort
Adenoma benign (non-cancerous tumour -secreting)
Anaemia (lack of blood)
Aortic valve sclerosis (narrowing of the aortic valve)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Bone pain
Cardiac murmur (an heart sound in valve abnormality)

60+:

Swelling
Anxiety
Dysarthria (speech disorder)
Fall
Hypertension (high blood pressure)
Injury
Muscle spasms (muscle contraction)
Musculoskeletal chest pain (pain in chest muscle or nerve or bones)
Neuropathy peripheral (surface nerve damage)
Rectal haemorrhage (bleeding from anus)

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 20 people, 32.79%
Restless Leg Syndrome (a powerful urge to move your legs): 17 people, 27.87%
Muscle Spasms (muscle contraction): 16 people, 26.23%
Upper Respiratory Tract Infection: 15 people, 24.59%
Bone Lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries): 15 people, 24.59%
Multiple Myeloma (cancer of the plasma cells): 15 people, 24.59%
High Blood Pressure: 12 people, 19.67%
Asthma: 11 people, 18.03%
Nausea (feeling of having an urge to vomit): 9 people, 14.75%
Depression: 8 people, 13.11%

* Approximation only. Some reports may have incomplete information.

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