Omnicef and Premarin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Omnicef (cefdinir) and Premarin (estrogens, conjugated). Common drug interactions include weight decreased among females and acute myocardial infarction among males.

The phase IV clinical study analyzes what interactions people have when they take Omnicef and Premarin. It is created by eHealthMe based on reports of 49 people who take the same drugs from the FDA, and is updated regularly.

What is Omnicef?

Omnicef has active ingredients of cefdinir. It is often used in sinusitis. eHealthMe is studying from 2,774 Omnicef users. Check the latest studies of Omnicef.

What is Premarin?

Premarin has active ingredients of estrogens, conjugated. It is often used in hormone replacement therapy. eHealthMe is studying from 99,630 Premarin users. Check the latest studies of Premarin.

On Aug, 09, 2026

49 people who take Omnicef and Premarin together, and have interactions are studied.

What are the common drug interactions of Omnicef and Premarin, by gender? *:

female:

Weight decreased
Atypical femur fracture
Biliary cirrhosis primary (primary biliary cirrhosis (pbc) is a long-term liver disease that damages the small bile ducts in the liver. the build-up of bile damages the liver)
Blood albumin decreased
Blood pressure increased
Chronic kidney disease
Constipation
Renal injury (kidney injury)
Anxiety
Pain

male:

Acute myocardial infarction (acute heart attack)
Angina pectoris (chest pain due to ischemia of the heart muscle)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Obesity (having too much body fat)
Post polio syndrome
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Type 2 diabetes mellitus
Blood triglycerides increased
Cardiomyopathy (weakening of the heart muscle)

What are the common drug interactions of Omnicef and Premarin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Atelectasis (partial or complete collapse of the lung)
Chest pain
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Dyspnoea (difficult or laboured respiration)
Oedema peripheral (superficial swelling)
Pain in extremity
Pleural effusion (water on the lungs)
Pulmonary embolism (blockage of the main artery of the lung)

30-39:

n/a

40-49:

Chronic kidney disease
Haematocrit increased
Haemoglobin increased
Hypoxia (low oxygen in tissues)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Lobar pneumonia (a form of pneumonia that affects a large and continuous area of the lobe of a lung)
Nephrogenic anaemia (anaemia due to kidney disease)
Papillary thyroid cancer
Personality disorder

50-59:

Blood pressure increased
Blood triglycerides increased
Cheilitis (infection of lips)
Chest pain
Contusion (a type of hematoma of tissue in which capillaries)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Cystitis glandularis (forming a timorous lesion with blueberry spots in the urinary bladder)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Emotional distress
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)

60+:

Constipation
Chronic kidney disease
Asterixis (flapping tremor, or liver flap)
Axillary mass
Benign neoplasm of thyroid gland (benign (non-cancerous) tumours of the thyroid gland)
Breast cancer
Breast mass
Breast pain
Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
Dysarthria (speech disorder)

What are the existing conditions these people have? *

High Blood Pressure: 23 people, 46.94%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 21 people, 42.86%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 16 people, 32.65%
Pain: 16 people, 32.65%
High Blood Cholesterol: 13 people, 26.53%
Hypersensitivity: 12 people, 24.49%
Muscle Spasms (muscle contraction): 10 people, 20.41%
Joint Pain: 9 people, 18.37%
Nausea (feeling of having an urge to vomit): 8 people, 16.33%
Depression: 8 people, 16.33%

* Approximation only. Some reports may have incomplete information.

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