Omnicef and Prozac drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Omnicef (cefdinir) and Prozac (fluoxetine hydrochloride). Common drug interactions include sleep disorder among females and attention deficit/hyperactivity disorder among males.

The phase IV clinical study analyzes what interactions people have when they take Omnicef and Prozac. It is created by eHealthMe based on reports of 46 people who take the same drugs from the FDA, and is updated regularly.

What is Omnicef?

Omnicef has active ingredients of cefdinir. It is often used in sinusitis. eHealthMe is studying from 2,774 Omnicef users. Check the latest studies of Omnicef.

What is Prozac?

Prozac has active ingredients of fluoxetine hydrochloride. It is often used in depression. eHealthMe is studying from 82,988 Prozac users. Check the latest studies of Prozac.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 26, 2026

46 people who take Omnicef and Prozac together, and have interactions are studied.

What are the common drug interactions of Omnicef and Prozac, by gender? *:

female:

Sleep disorder
Social avoidant behaviour (avoiding social connection a personality disorder)
Spondylolisthesis (displacement of a vertebra or the vertebral column in relation to the vertebrae below)
Tricuspid valve incompetence (inefficient heart valve)
Type 2 diabetes mellitus
Back pain
Cardiac failure congestive
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Carotid artery stenosis (narrowing of carotid artery)
Complex regional pain syndrome (long lasting pain condition most often affecting one of the limbs (arms, legs, hands, or feet))

male:

Attention deficit/hyperactivity disorder
B-cell lymphoma (blood cancer affecting b cells)
Lung neoplasm (tumour of lung)
Pyrexia (fever)
Reflux oesophagitis (an oesophageal mucosal injury that occurs of gastric contents into the oesophagus)
Rhinitis allergic (inflammation of the nasal airways due to allergy)
Suicidal ideation
Anger
Pharyngitis (inflammation of the pharynx, causing a sore throat)
Psychotic disorder

What are the common drug interactions of Omnicef and Prozac, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Attention deficit/hyperactivity disorder
B-cell lymphoma (blood cancer affecting b cells)
Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
Conjunctivitis (pink eye)
Cough
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
Eczema eyelids (patches of skin become rough and inflamed, with itching and bleeding blisters on eyelid)
Lung neoplasm (tumour of lung)
Pyrexia (fever)
Reflux oesophagitis (an oesophageal mucosal injury that occurs of gastric contents into the oesophagus)

10-19:

Cholecystitis (infection of gallbladder)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Drug toxicity
Gait disturbance
Joint stiffness
Prostatitis (inflammation of the prostate gland)
Therapeutic response decreased (less preventive response)
Urinary incontinence (inability to control the flow of urine and involuntary urination)

20-29:

Complex regional pain syndrome (long lasting pain condition most often affecting one of the limbs (arms, legs, hands, or feet))
Neuropathy peripheral (surface nerve damage)
Rhinitis allergic (inflammation of the nasal airways due to allergy)
Seasonal allergy (allergic condition due to certain season)
Skin papilloma (a general medical term for a tumour of the skin or mucous membrane with finger-like projections)
Weight increased
Wheezing (a high-pitched whistling sound made while you breath)
Dyspnoea (difficult or laboured respiration)
Migraine (headache)
Overdose

30-39:

Chronic kidney disease
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)

40-49:

Pain
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Thrombophlebitis superficial (swelling (inflammation) of a superficial vein caused by a blood clot)
Thrombosis (formation of a blood clot inside a blood vessel)
Acute myocardial infarction (acute heart attack)
Chest pain
Hot flush (sudden feelings of heat)
Myocardial ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased)
Accident
Angiopathy (generic term for a disease of the blood vessels)

50-59:

Intervertebral disc degeneration (spinal disc degeneration)
Joint sprain (an injury to joint surrounding flexible fibres)
Mitral valve calcification (calcium deposit in mitral valve)
Nephrocalcinosis (a condition in which calcium levels in the kidneys are increased)
Neuropathy peripheral (surface nerve damage)
Oropharyngeal pain
Palpitations (feelings or sensations that your heart is pounding or racing)
Pancreatitis relapsing
Panniculitis (inflammation of the subcutaneous fat)
Pharyngitis (inflammation of the pharynx, causing a sore throat)

60+:

Cough
Asthenia (weakness)
Renal injury (kidney injury)
Thrombosis (formation of a blood clot inside a blood vessel)
Abasia (inability to walk)
Azotaemia (excess of urea or other nitrogenous compounds in the blood)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Device dislocation
Encephalopathy (functioning of the brain is affected by some agent or condition)
Fall

What are the existing conditions these people have? *

Pain: 12 people, 26.09%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 8 people, 17.39%
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 8 people, 17.39%
Premenstrual Syndrome: 7 people, 15.22%
High Blood Cholesterol: 6 people, 13.04%
Stress And Anxiety: 4 people, 8.70%
High Blood Pressure: 4 people, 8.70%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 4 people, 8.70%
Asthma: 4 people, 8.70%
Urinary Retention (the inability to completely or partially empty the bladder): 3 people, 6.52%

* Approximation only. Some reports may have incomplete information.

Do you take Omnicef and Prozac?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously