Omnicef and Robitussin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Omnicef (cefdinir) and Robitussin (guaifenesin). Common drug interactions include cardiac failure congestive among females and acute respiratory failure among males.

The phase IV clinical study analyzes what interactions people have when they take Omnicef and Robitussin. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Omnicef?

Omnicef has active ingredients of cefdinir. It is often used in sinusitis. eHealthMe is studying from 2,774 Omnicef users. Check the latest studies of Omnicef.

What is Robitussin?

Robitussin has active ingredients of guaifenesin. eHealthMe is studying from 3,532 Robitussin users. Check the latest studies of Robitussin.

On Jul, 26, 2026

14 people who take Omnicef and Robitussin together, and have interactions are studied.

Omnicef and Robitussin drug interactions.

What are the common drug interactions of Omnicef and Robitussin, by gender? *:

female:

Cardiac failure congestive
Dehydration (dryness resulting from the removal of water)
Hypotension (abnormally low blood pressure)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Decreased appetite
Dyspnoea exertional (breathlessness or shortness of breath)
Haemorrhoids (a swollen vein or group of veins in the region of the anus)
Malaise (a feeling of general discomfort or uneasiness)
Pneumonia

male:

Acute respiratory failure
Anaemia (lack of blood)
Renal failure (kidney dysfunction)
Thrombophlebitis superficial (swelling (inflammation) of a superficial vein caused by a blood clot)
Adverse drug reaction
Anxiety
Asthma
Cardiac disorder
Cardiomegaly (increased size of heart than normal)
Cough

What are the common drug interactions of Omnicef and Robitussin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Ear pain
Pyrexia (fever)

10-19:

n/a

20-29:

Anxiety
Asthma
Cardiomegaly (increased size of heart than normal)
Cough
Drug abuse
Drug dependence
Hepatosplenomegaly (enlargement of both the liver and the spleen)
Insomnia (sleeplessness)
Intervertebral disc protrusion (spinal disc protrusion)
Ligament sprain (ligament stretched)

30-39:

n/a

40-49:

Chronic kidney disease
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)

50-59:

n/a

60+:

Cardiac failure congestive
Dehydration (dryness resulting from the removal of water)
Renal failure acute (rapid kidney dysfunction)
Blood pressure systolic increased
Carotid artery stenosis (narrowing of carotid artery)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Contusion (a type of hematoma of tissue in which capillaries)
Dyspepsia (indigestion)
Excoriation (to tear or wear off the skin of)
Fatigue (feeling of tiredness)

What are the existing conditions these people have? *

Pain: 3 people, 21.43%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 21.43%
High Blood Pressure: 3 people, 21.43%
Chest Pain: 2 people, 14.29%
Metastatic Renal Cell Carcinoma (spreadable kidney cell tumour): 2 people, 14.29%
Wheezing (a high-pitched whistling sound made while you breath): 1 person, 7.14%
High Blood Cholesterol: 1 person, 7.14%
Blood Cholesterol Decreased: 1 person, 7.14%
Cough: 1 person, 7.14%
Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

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