Omnicef and Vitamin d drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Omnicef (cefdinir) and Vitamin d (ergocalciferol). Common drug interactions include hypophosphataemia among females and renal failure among males.

The phase IV clinical study analyzes what interactions people have when they take Omnicef and Vitamin d. It is created by eHealthMe based on reports of 83 people who take the same drugs from the FDA, and is updated regularly.

What is Omnicef?

Omnicef has active ingredients of cefdinir. It is often used in sinusitis. eHealthMe is studying from 2,774 Omnicef users. Check the latest studies of Omnicef.

What is Vitamin d?

Vitamin d has active ingredients of ergocalciferol. It is often used in low vitamin d. eHealthMe is studying from 294,095 Vitamin d users. Check the latest studies of Vitamin d.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 22, 2026

83 people who take Omnicef and Vitamin d together, and have interactions are studied.

Omnicef and Vitamin d drug interactions.

What are the common drug interactions of Omnicef and Vitamin D, by gender? *:

female:

  1. Hypophosphataemia (electrolyte disturbance in which there is an abnormally low level of phosphate in the blood)
  2. Impaired self-care
  3. Spinal compression fracture (fracture due to spinal compression on bone)
  4. Urinary tract infection
  5. Asthenia (weakness)
  6. Depression
  7. Gastric ulcer (stomach ulcer)
  8. Back pain
  9. Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
  10. Duodenal ulcer

male:

  1. Renal failure (kidney dysfunction)
  2. Malaise (a feeling of general discomfort or uneasiness)
  3. Lung disorder (lung disease)
  4. Pleural effusion (water on the lungs)
  5. Decreased appetite
  6. Pneumonia
  7. Nephrotic syndrome (kidney disease with proteinuria, hypoalbuminemia, and oedema)
  8. Renal tubular necrosis (death of kidney tubules)
  9. Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
  10. Acute febrile neutrophilic dermatosis (skin disease characterized by the sudden onset of fever, leukocytosis, and tender)

What are the common drug interactions of Omnicef and Vitamin D, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Hypophagia (reduced food intake)
  2. Influenza
  3. Respiratory distress (difficulty in breathing)
  4. Adenovirus infection
  5. Dehydration (dryness resulting from the removal of water)
  6. Hepatic enzyme increased
  7. Hypoglycaemia (deficiency of glucose in the bloodstream)
  8. Nausea (feeling of having an urge to vomit)
  9. Pneumonia
  10. Pneumonia respiratory syncytial viral (respiratory syncytial virus (rsv) is a very common virus that leads to mild, cold-like symptoms in adults and older healthy children)

10-19:

  1. Headache (pain in head)
  2. Choking (mechanical obstruction of the flow of air from the environment into the lungs)
  3. Decreased appetite
  4. Dysphemia (stammering or stuttering)
  5. Fall
  6. Malaise (a feeling of general discomfort or uneasiness)
  7. Nausea (feeling of having an urge to vomit)
  8. Pain in extremity
  9. Photophobia (extreme sensitivity to light)
  10. Disease progression

20-29:

  1. Adverse drug reaction
  2. Back pain
  3. Chronic kidney disease
  4. Confusional state
  5. Dizziness
  6. Emotional distress
  7. Fatigue (feeling of tiredness)
  8. Fear
  9. Hallucination (an experience involving the perception of something not present)
  10. Hypoaesthesia (reduced sense of touch or sensation)

30-39:

  1. Chronic kidney disease
  2. Nephrogenic anaemia (anaemia due to kidney disease)
  3. Renal failure (kidney dysfunction)

40-49:

  1. Chronic kidney disease
  2. Nephrotic syndrome (kidney disease with proteinuria, hypoalbuminemia, and oedema)
  3. Renal failure (kidney dysfunction)
  4. Renal tubular necrosis (death of kidney tubules)
  5. Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
  6. Fatigue (feeling of tiredness)
  7. Lymphocyte count decreased
  8. Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
  9. Urine abnormality
  10. Acne (skin problems that cause pimples)

50-59:

  1. Anaemia (lack of blood)
  2. Fear of disease
  3. Mania (a state of abnormally elevated or irritable mood)
  4. Panic disorder
  5. Back pain
  6. Dizziness
  7. Headache (pain in head)
  8. Hepatic steatosis (fatty liver disease)
  9. Nausea (feeling of having an urge to vomit)
  10. Abdominal distension

60+:

  1. Nausea (feeling of having an urge to vomit)
  2. Anxiety
  3. Asthenia (weakness)
  4. Chronic kidney disease
  5. Dysphagia (a condition in which swallowing is difficult or painful)
  6. Fatigue (feeling of tiredness)
  7. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  8. Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream)
  9. Aphasia (damage to the parts of the brain that control language)
  10. Device occlusion

What are the existing conditions these people have? *

  1. Pain: 32 people, 38.55%
  2. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 22 people, 26.51%
  3. High Blood Pressure: 14 people, 16.87%
  4. Nausea (feeling of having an urge to vomit): 14 people, 16.87%
  5. High Blood Cholesterol: 12 people, 14.46%
  6. Rickets (softening of bones): 10 people, 12.05%
  7. Cough: 10 people, 12.05%
  8. Neuralgia (pain in one or more nerves): 10 people, 12.05%
  9. Fibromyalgia (a long-term condition which causes pain all over the body): 9 people, 10.84%
  10. Urinary Tract Infection: 8 people, 9.64%

* Approximation only. Some reports may have incomplete information.

Do you take Omnicef and Vitamin d?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Omnicef and Vitamin d:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Omnicef:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Vitamin d:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Omnicef and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Vitamin d and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on cefdinir and ergocalciferol (the active ingredients of Omnicef and Vitamin d, respectively), and Omnicef and Vitamin d (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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