Ondansetron and Synjardy drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ondansetron (ondansetron) and Synjardy (empagliflozin; metformin hydrochloride). Common drug interactions include fatigue among females and abdominal discomfort among males.

The phase IV clinical study analyzes what interactions people have when they take Ondansetron and Synjardy. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Ondansetron?

Ondansetron has active ingredients of ondansetron. It is often used in nausea. eHealthMe is studying from 122,738 Ondansetron users. Check the latest studies of Ondansetron.

What is Synjardy?

Synjardy has active ingredients of empagliflozin; metformin hydrochloride. eHealthMe is studying from 2,928 Synjardy users. Check the latest studies of Synjardy.

On Jul, 12, 2026

23 people who take Ondansetron and Synjardy together, and have interactions are studied.

Ondansetron and Synjardy drug interactions.

What are the common drug interactions of Ondansetron and Synjardy, by gender? *:

female:

Fatigue (feeling of tiredness)
Fungal infection
Immunoglobulins increased
Infusion site pruritus (severe itching at infusion site)
Injection site erythema (redness at injection site)
Injection site swelling
Lower respiratory tract infection
Nasopharyngitis (inflammation of the nasopharynx)
Sinusitis (inflammation of sinus)
Cough

male:

Abdominal discomfort
Asthma
Renal disorder (kidney disease)
Scrotal abscess (pus in scrotum)
Spinal disorder (disease of spine a back bone)
Tendon rupture (tear of tendon)
Back pain
Nephrolithiasis (calculi in the kidneys)
Restless legs syndrome (a powerful urge to move your legs)
Surgery

What are the common drug interactions of Ondansetron and Synjardy, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Scrotal abscess (pus in scrotum)

50-59:

Abdominal discomfort
Abnormal dreams
Asthma
Back pain
Blood sodium decreased
Enuresis (repeated inability to control urination)
Fatigue (feeling of tiredness)
Hypersomnia (excessive daytime sleepiness (eds))
Ileus (a painful obstruction of the ileum or other part of the intestine)
Nephrolithiasis (calculi in the kidneys)

60+:

Fatigue (feeling of tiredness)
Immunoglobulins increased
Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
Dyspnoea (difficult or laboured respiration)
Fungal infection
Infusion site haemorrhage (bleeding from infusion site)
Injection site pain
Irritability
Muscle strain (an injury to a muscle in which the muscle fibres tear)
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 6 people, 26.09%
Primary Immunodeficiency Syndrome: 5 people, 21.74%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 13.04%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 13.04%
Drowsiness: 2 people, 8.70%
Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 2 people, 8.70%
Back Pain: 2 people, 8.70%
Abdominal Discomfort: 2 people, 8.70%

* Approximation only. Some reports may have incomplete information.

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