Trovan and Diflucan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Trovan (trovafloxacin mesylate) and Diflucan (fluconazole). Common drug interactions include pyrexia among females and pyrexia among males.

The phase IV clinical study analyzes what interactions people have when they take Trovan and Diflucan. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Trovan?

Trovan has active ingredients of trovafloxacin mesylate. eHealthMe is studying from 2,227 Trovan users. Check the latest studies of Trovan.

What is Diflucan?

Diflucan has active ingredients of fluconazole. It is often used in vaginal yeast infection. eHealthMe is studying from 28,471 Diflucan users. Check the latest studies of Diflucan.

On Jul, 12, 2026

20 people who take Trovan and Diflucan together, and have interactions are studied.

What are the common drug interactions of Trovan and Diflucan, by gender? *:

female:

Pyrexia (fever)
Anxiety
Depression
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
Hepatic failure (liver failure)
Hypersensitivity
Insomnia (sleeplessness)
Multi-organ failure (multisystem organ failure)
Neutropenia (an abnormally low number of neutrophils)
Rash generalised (rash on most of body parts)

male:

Pyrexia (fever)
Bradycardia (abnormally slow heart action)
Ventricular fibrillation (abnormally irregular heart rhythm)
Vomiting
Abdominal pain
Application site reaction
Blood bilirubin increased
Blood creatinine increased
Blood culture positive
Blood urea increased

What are the common drug interactions of Trovan and Diflucan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Vomiting
Abdominal pain
Anxiety
Depression
Diarrhoea
Face oedema (swelling of face)
Hand and foot syndrome
Hepatic failure (liver failure)
Hepatocellular damage (liver damage)
Insomnia (sleeplessness)

40-49:

Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart)

50-59:

Ejection fraction (the percentage of blood that is pumped out of a filled ventricle as a result of a heartbeat)
Multi-organ failure (multisystem organ failure)
Pulmonary oedema (fluid accumulation in the lungs)
Renal failure (kidney dysfunction)
Ventricular fibrillation (abnormally irregular heart rhythm)
Blood bilirubin increased
Blood creatinine increased
Blood urea increased
Difficulty in walking
Dysarthria (speech disorder)

60+:

Application site reaction
Diarrhoea
Oedema peripheral (superficial swelling)
Pain
Superinfection
Tachycardia (a heart rate that exceeds the range of 100 beats/min)

What are the existing conditions these people have? *

Ill-Defined Disorder: 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

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