Opdivo and Cardura drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Opdivo (nivolumab) and Cardura (doxazosin mesylate). Common drug interactions include inflammation among females and acute respiratory failure among males.
The phase IV clinical study analyzes what interactions people have when they take Opdivo and Cardura. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.
What is Opdivo?
Opdivo has active ingredients of nivolumab. eHealthMe is studying from 56,331 Opdivo users. Check the latest studies of Opdivo.
What is Cardura?
Cardura has active ingredients of doxazosin mesylate. It is often used in high blood pressure. eHealthMe is studying from 20,379 Cardura users. Check the latest studies of Cardura.
13 people who take Opdivo and Cardura together, and have interactions are studied.

What are the common drug interactions of Opdivo and Cardura, by gender? *:
female:
- Inflammation
- Panniculitis (inflammation of the subcutaneous fat)
- Pneumonitis (inflammation of the walls of the alveoli in the lungs)
- Pyrexia (fever)
- Thrombocytopenia (decrease of platelets in blood)
male:
- Acute respiratory failure
- Asthenia (weakness)
- Confusional state
- Cough
- Diarrhoea
- Dry mouth
- Eating disorder
- Eye disorder
- Hypoaesthesia (reduced sense of touch or sensation)
- Nervous system disorder (a general class of medical conditions affecting the nervous system)
What are the common drug interactions of Opdivo and Cardura, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Inflammation
- Panniculitis (inflammation of the subcutaneous fat)
- Pneumonitis (inflammation of the walls of the alveoli in the lungs)
- Pyrexia (fever)
60+:
- Acute respiratory failure
- Drug intolerance (drug sensitivity)
- Dehydration (dryness resulting from the removal of water)
- Dysphonia (speech disorder attributable to a disorder of phonation)
- Epistaxis (bleed from the nose)
- Gamma-glutamyltransferase increased
- Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
- Intervertebral disc compression (spinal disc compression)
- Nausea (feeling of having an urge to vomit)
What are the existing conditions these people have? *
- Pain: 3 people, 23.08%
- Malignant Melanoma (skin cancer rises from melancytes): 3 people, 23.08%
- Angiosarcoma (cancer of endothelial-type cells that line vessel walls): 2 people, 15.38%
- Sleep Disorder: 2 people, 15.38%
- Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 2 people, 15.38%
- Prostate Cancer: 2 people, 15.38%
- Pancreatic Neuroendocrine Tumor: 2 people, 15.38%
- Oral Disorder (mouth disease): 2 people, 15.38%
- Neuroendocrine Carcinoma Of The Skin (a rare type of cancer that forms on or just beneath the skin, usually in parts of the body that have been exposed to the sun): 2 people, 15.38%
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 15.38%
* Approximation only. Some reports may have incomplete information.
Do you take Opdivo and Cardura?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Opdivo and Cardura:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Opdivo:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Cardura:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Opdivo and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Cardura and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on nivolumab and doxazosin mesylate (the active ingredients of Opdivo and Cardura, respectively), and Opdivo and Cardura (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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