Optimark and Regular insulin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Optimark (gadoversetamide) and Regular insulin (insulin pork). Common drug interactions include injury among females and nephrogenic systemic fibrosis among males.

The phase IV clinical study analyzes what interactions people have when they take Optimark and Regular insulin. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Optimark?

Optimark has active ingredients of gadoversetamide. eHealthMe is studying from 3,055 Optimark users. Check the latest studies of Optimark.

What is Regular insulin?

Regular insulin has active ingredients of insulin pork. It is often used in type 1 diabetes. eHealthMe is studying from 2,848 Regular insulin users. Check the latest studies of Regular insulin.

On Jul, 26, 2026

13 people who take Optimark and Regular insulin together, and have interactions are studied.

Optimark and Regular insulin drug interactions.

What are the common drug interactions of Optimark and Regular Insulin, by gender? *:

female:

Injury
Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
Pain
Activities of daily living impaired
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Emotional distress
Joint range of motion decreased (disease of joint movement)
Mobility decreased (ability to move is reduced)
Pruritus (severe itching of the skin)

male:

Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
Pain
General physical health deterioration (weak health status)
Injury
Muscle contracture (a permanent shortening of a muscle)
Scar
Asthma
Central nervous system lesion (an abnormality in tissue of brain or spinal cord)
Extremity contracture (permanent shortening of a muscle or joint of arms and legs)
Fatigue (feeling of tiredness)

What are the common drug interactions of Optimark and Regular Insulin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
Asthma
Central nervous system lesion (an abnormality in tissue of brain or spinal cord)
Depression
Extremity contracture (permanent shortening of a muscle or joint of arms and legs)
Fatigue (feeling of tiredness)
Joint contracture (a permanent shortening of a muscle or joint)
Joint stiffness
Memory impairment
Mobility decreased (ability to move is reduced)

40-49:

n/a

50-59:

Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
Pain
Anxiety
Emotional distress
Mobility decreased (ability to move is reduced)
Skin induration (an abnormally hard spot or area on the skin)
Skin hypertrophy (skin cells enlarges)
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Depression
Gait disturbance

60+:

Hypoaesthesia (reduced sense of touch or sensation)
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
Oedema peripheral (superficial swelling)
Pain
Peau d'orange (orange peel skin)
Skin hyperpigmentation (disorders affect the colour of your skin)
Skin hypertrophy (skin cells enlarges)
Skin tightness

What are the existing conditions these people have? *

Nuclear Magnetic Resonance Imaging Brain: 6 people, 46.15%
High Blood Pressure: 6 people, 46.15%
Fibromyalgia (a long-term condition which causes pain all over the body): 6 people, 46.15%
Diabetes: 6 people, 46.15%
Pain: 5 people, 38.46%
Eye Disorder: 5 people, 38.46%
Sleep Disorder: 4 people, 30.77%
Analgesia: 2 people, 15.38%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 7.69%
Intraocular Pressure Increased: 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

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