Optivar and Neurontin drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Optivar (azelastine hydrochloride) and Neurontin (gabapentin). Common drug interactions include pneumonia among females and acute respiratory failure among males.
The phase IV clinical study analyzes what interactions people have when they take Optivar and Neurontin. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.
What is Optivar?
Optivar has active ingredients of azelastine hydrochloride. eHealthMe is studying from 367 Optivar users. Check the latest studies of Optivar.
What is Neurontin?
Neurontin has active ingredients of gabapentin. It is often used in neuralgia. eHealthMe is studying from 107,468 Neurontin users. Check the latest studies of Neurontin.
17 people who take Optivar and Neurontin together, and have interactions are studied.

What are the common drug interactions of Optivar and Neurontin, by gender? *:
female:
- Pneumonia
- Drug effect delayed
- Dyspepsia (indigestion)
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Diarrhoea
- Fatigue (feeling of tiredness)
- Hepatitis (inflammation of the liver)
- Hypocalcaemia (levels of calcium in blood serum are abnormally low)
- Lung infection
- Lung neoplasm malignant (cancer tumour of lung)
male:
- Acute respiratory failure
- Anaemia (lack of blood)
- Proteinuria (presence of protein in the urine)
- Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Vomiting
- Haemorrhage (bleeding)
- Headache (pain in head)
- Nausea (feeling of having an urge to vomit)
- Abdominal discomfort
What are the common drug interactions of Optivar and Neurontin, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Throat irritation
- Urticaria (rash of round, red welts on the skin that itch intensely)
- Wheezing (a high-pitched whistling sound made while you breath)
50-59:
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Oedema peripheral (superficial swelling)
- Osteoarthritis (a joint disease caused by cartilage loss in a joint)
- Pneumonia
- Sputum discoloured
- Balance disorder
- Cataract (clouding of the lens inside the eye)
- Constipation
- Cough
- Dry eye (lack of adequate tears)
60+:
- Vomiting
- Acute respiratory failure
- Myositis (inflammation of the muscles)
- Proteinuria (presence of protein in the urine)
- Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Diarrhoea
- Drug effect delayed
- Dyspepsia (indigestion)
- Haemorrhage (bleeding)
What are the existing conditions these people have? *
- Pain: 7 people, 41.18%
- Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 6 people, 35.29%
- Metastases To Central Nervous System (cancer spreads to central nervous system): 5 people, 29.41%
- Dry Eyes (lack of adequate tears): 5 people, 29.41%
- Oedema (fluid collection in tissue): 5 people, 29.41%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 17.65%
- Depression: 3 people, 17.65%
- Asthma: 3 people, 17.65%
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 17.65%
- Hypersensitivity: 3 people, 17.65%
* Approximation only. Some reports may have incomplete information.
Do you take Optivar and Neurontin?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Optivar and Neurontin:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Optivar:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Neurontin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Optivar and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Neurontin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- de Landaluce, L. O., Carbonell, P., Asensio, C., Escoda, N., López, P., & Laporte, J. R. , "Gabapentin and Pregabalin and Risk of Atrial Fibrillation in the Elderly: A Population-Based Cohort Study in an Electronic Prescription Database", Drug safety, 2018 Jan .
- Scarff JR, "The Potential for Somnambulism Associated with Gabapentin", The Internet Journal of Psychiatry, 2014 Jan .
- de Landaluce, L. O., Carbonell, P., Asensio, C., Escoda, N., López, P., & Laporte, J. R. , "Gabapentin and Pregabalin and Risk of Atrial Fibrillation in the Elderly: A Population-Based Cohort Study in an Electronic Prescription Database", Drug safety, 2018 Jan .
- Scarff JR, "The Potential for Somnambulism Associated with Gabapentin", The Internet Journal of Psychiatry, 2014 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on azelastine hydrochloride and gabapentin (the active ingredients of Optivar and Neurontin, respectively), and Optivar and Neurontin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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