Oracea and Lasix drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Oracea (doxycycline) and Lasix (furosemide). Common drug interactions include coronary artery disease among females and hyponatraemia among males.
The phase IV clinical study analyzes what interactions people have when they take Oracea and Lasix. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.
What is Oracea?
Oracea has active ingredients of doxycycline. It is often used in rosacea. eHealthMe is studying from 1,272 Oracea users. Check the latest studies of Oracea.
What is Lasix?
Lasix has active ingredients of furosemide. It is often used in swelling. eHealthMe is studying from 210,439 Lasix users. Check the latest studies of Lasix.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
24 people who take Oracea and Lasix together, and have interactions are studied.

What are the common drug interactions of Oracea and Lasix, by gender? *:
female:
- Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
- Lower gastrointestinal haemorrhage (bleeding in the large intestine, rectum, or anus is called lower gi bleeding)
- Post-traumatic stress disorder
- Acute respiratory failure
- Cardiac arrest
- Exostosis (formation of new bone on the surface of a bone)
- Gastrointestinal viral infection (virus infection of gastrointestinal tract)
- Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
- Renal tubular necrosis (death of kidney tubules)
male:
- Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
- Urinary tract infection
- Anaemia (lack of blood)
- Back pain
- Confusional state
- Delirium (wild excitement)
- Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
- Pneumonia
What are the common drug interactions of Oracea and Lasix, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Cardiac myxoma (tumour of the heart in adults)
- Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
- Post-traumatic stress disorder
- Exostosis (formation of new bone on the surface of a bone)
- Gastrointestinal viral infection (virus infection of gastrointestinal tract)
- Viral infection
60+:
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
- Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
- Back pain
- Balance disorder
- Cardiac arrest
- Confusional state
- Delirium (wild excitement)
- Diabetes mellitus inadequate control
- Drug hypersensitivity
- Dysarthria (speech disorder)
What are the existing conditions these people have? *
- Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 6 people, 25.00%
- High Blood Pressure: 6 people, 25.00%
- High Blood Cholesterol: 4 people, 16.67%
- Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 12.50%
- Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 3 people, 12.50%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 12.50%
- Chest Pain: 3 people, 12.50%
- Nausea (feeling of having an urge to vomit): 2 people, 8.33%
- Motion Sickness (travel sickness): 2 people, 8.33%
- Iron Deficiency Anaemia: 2 people, 8.33%
* Approximation only. Some reports may have incomplete information.
Do you take Oracea and Lasix?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Oracea and Lasix:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Oracea:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Lasix:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Oracea and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Lasix and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Ochoa PS, Fisher T, "A 7‐Year Case of Furosemide‐Induced Immune Thrombocytopenia", Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 2013 Jul .
- Dmour HH, Zayadeen AR, Shawagfeh JS, "Effect of Long Term Prophylaxis of Antimalarial Drug (Doxycycline) on Liver Span by Ultrasound", Middle East Journal of Internal Medicine, 2013 Jan .
- Ochoa PS, Fisher T, "A 7‐Year Case of Furosemide‐Induced Immune Thrombocytopenia", Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 2013 Jul .
- Dmour HH, Zayadeen AR, Shawagfeh JS, "Effect of Long Term Prophylaxis of Antimalarial Drug (Doxycycline) on Liver Span by Ultrasound", Middle East Journal of Internal Medicine, 2013 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on doxycycline and furosemide (the active ingredients of Oracea and Lasix, respectively), and Oracea and Lasix (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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