Oracea and Lorazepam drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Oracea (doxycycline) and Lorazepam (lorazepam). Common drug interactions include weight increased among females and compartment syndrome among males.

The phase IV clinical study analyzes what interactions people have when they take Oracea and Lorazepam. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Oracea?

Oracea has active ingredients of doxycycline. It is often used in rosacea. eHealthMe is studying from 1,272 Oracea users. Check the latest studies of Oracea.

What is Lorazepam?

Lorazepam has active ingredients of lorazepam. It is often used in stress and anxiety. eHealthMe is studying from 165,639 Lorazepam users. Check the latest studies of Lorazepam.



On Jul, 26, 2026

20 people who take Oracea and Lorazepam together, and have interactions are studied.

Oracea and Lorazepam drug interactions.

What are the common drug interactions of Oracea and Lorazepam, by gender? *:

female:

  1. Weight increased
  2. Chronic kidney disease
  3. Erythema (redness of the skin)
  4. Flushing (the warm, red condition of human skin)
  5. Nausea (feeling of having an urge to vomit)
  6. Rash maculo-papular (red area on the skin that is covered with small confluent bumps)
  7. Abdominal pain upper
  8. Breast discharge
  9. Breast mass
  10. Breast necrosis (death of cells or tissues through injury or disease in beast)

male:

  1. Compartment syndrome (painful condition that occurs when pressure within the muscles builds to dangerous levels)
  2. Skin discolouration (change of skin colour)
  3. Somnolence (a state of near-sleep, a strong desire for sleep)

What are the common drug interactions of Oracea and Lorazepam, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Abdominal pain upper
  2. Dry mouth
  3. Dysgeusia (disorder of the sense of taste)
  4. Nausea (feeling of having an urge to vomit)

40-49:

  1. Diarrhoea
  2. Flushing (the warm, red condition of human skin)
  3. Nausea (feeling of having an urge to vomit)
  4. Vomiting

50-59:

  1. Skin burning sensation
  2. Skin warm
  3. Tinnitus (a ringing in the ears)
  4. Erythema (redness of the skin)
  5. Eye irritation
  6. Flushing (the warm, red condition of human skin)
  7. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  8. Paraesthesia oral (sensation of tingling, tickling, prickling, pricking, or burning of a person's oral with no apparent long-term physical effect)
  9. Rash macular (small, flat red spots)

60+:

  1. Rash maculo-papular (red area on the skin that is covered with small confluent bumps)
  2. Compartment syndrome (painful condition that occurs when pressure within the muscles builds to dangerous levels)
  3. Skin discolouration (change of skin colour)
  4. Somnolence (a state of near-sleep, a strong desire for sleep)

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 11 people, 55.00%
  2. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 6 people, 30.00%
  3. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 25.00%
  4. Herpes Simplex (herpes simplex is a common viral infection): 2 people, 10.00%
  5. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 10.00%
  6. Thyroid Diseases: 2 people, 10.00%
  7. Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking): 2 people, 10.00%
  8. Constipation: 2 people, 10.00%
  9. Visual Impairment: 2 people, 10.00%
  10. Oral Discomfort (pain or irritation in mouth): 2 people, 10.00%

* Approximation only. Some reports may have incomplete information.

Do you take Oracea and Lorazepam?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Oracea and Lorazepam:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Oracea:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Lorazepam:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Oracea and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lorazepam and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on doxycycline and lorazepam (the active ingredients of Oracea and Lorazepam, respectively), and Oracea and Lorazepam (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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