Orenitram and Humalog drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Orenitram (treprostinil) and Humalog (insulin lispro recombinant). Common drug interactions include cough among females and headache among males.

The phase IV clinical study analyzes what interactions people have when they take Orenitram and Humalog. It is created by eHealthMe based on reports of 56 people who take the same drugs from the FDA, and is updated regularly.

What is Orenitram?

Orenitram has active ingredients of treprostinil. eHealthMe is studying from 17,714 Orenitram users. Check the latest studies of Orenitram.

What is Humalog?

Humalog has active ingredients of insulin lispro recombinant. It is often used in diabetes. eHealthMe is studying from 137,127 Humalog users. Check the latest studies of Humalog.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

56 people who take Orenitram and Humalog together, and have interactions are studied.

Orenitram and Humalog drug interactions.

What are the common drug interactions of Orenitram and Humalog, by gender? *:

female:

Cough
Device failure
Drug ineffective
Frequent bowel movements
Gait disturbance
Injection site haemorrhage (bleeding from injection site)
Mucosal haemorrhage (bleeding from mucous membrane)
Night sweats (sweating in night)
Pancreatic disorder
Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs)

male:

Headache (pain in head)
Head discomfort
Blood pressure increased
Cardiac failure
Confusional state
Diarrhoea
Dyspnoea exertional (breathlessness or shortness of breath)
Fatigue (feeling of tiredness)
Flushing (the warm, red condition of human skin)
Hospitalisation

What are the common drug interactions of Orenitram and Humalog, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Impaired gastric emptying
Nausea (feeling of having an urge to vomit)
Vomiting
Abdominal pain
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Device related infection

50-59:

Headache (pain in head)
Diarrhoea
Malaise (a feeling of general discomfort or uneasiness)
Nausea (feeling of having an urge to vomit)
Retching (strong involuntary effort to vomit)
Abdominal pain
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Device related infection
Dyspnoea (difficult or laboured respiration)
Hemiparesis (weakness on one side of the body)

60+:

Nausea (feeling of having an urge to vomit)
Pneumonia
Vomiting
Respiratory failure (inadequate gas exchange by the respiratory system)
Blood pressure decreased
Cardiac failure congestive
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Sinus node dysfunction (a group of abnormal heart rhythms)
Syncope (loss of consciousness with an inability to maintain postural tone)
Fall

What are the existing conditions these people have? *

Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 47 people, 83.93%
Nausea (feeling of having an urge to vomit): 6 people, 10.71%
High Blood Pressure: 5 people, 8.93%
Neuropathy Peripheral (surface nerve damage): 4 people, 7.14%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 4 people, 7.14%
High Blood Cholesterol: 4 people, 7.14%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 7.14%
Cardiac Failure: 4 people, 7.14%
Sleep Disorder: 3 people, 5.36%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 3 people, 5.36%

* Approximation only. Some reports may have incomplete information.

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