Osmoprep and Profen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Osmoprep (sodium phosphate, dibasic, anhydrous; sodium phosphate, monobasic, monohydrate) and Profen (ibuprofen). Common drug interactions include nephrocalcinosis among females and fall among males.

The phase IV clinical study analyzes what interactions people have when they take Osmoprep and Profen. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Osmoprep?

Osmoprep has active ingredients of sodium phosphate, dibasic, anhydrous; sodium phosphate, monobasic, monohydrate. It is often used in colonoscopy abnormal. eHealthMe is studying from 416 Osmoprep users. Check the latest studies of Osmoprep.

What is Profen?

Profen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 245,311 Profen users. Check the latest studies of Profen.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 14, 2026

14 people who take Osmoprep and Profen together, and have interactions are studied.

What are the common drug interactions of Osmoprep and Profen, by gender? *:

female:

Nephrocalcinosis (a condition in which calcium levels in the kidneys are increased)
Renal failure (kidney dysfunction)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Kidney fibrosis (excess fibrous connective tissue in kidney)
Nausea (feeling of having an urge to vomit)
Renal failure acute (rapid kidney dysfunction)
Renal tubular atrophy (wasting of kidney tubules)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
Arteriosclerosis (thickening and hardening of arteries)
Headache (pain in head)

male:

Fall
Androgen deficiency
Foot fracture
Gastric disorder (disease of stomach)
Humerus fracture (injury to the upper arm bone)
Myalgia (muscle pain)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Osteoporosis (bones weak and more likely to break)
Pain in extremity
Periarthritis (inflammation of the external coats of an artery and of the tissues around the artery)

What are the common drug interactions of Osmoprep and Profen, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Renal failure acute (rapid kidney dysfunction)
Abasia (inability to walk)
Arachnoiditis (neuropathic disease caused by inflammation of the arachnoid)
Bladder dysfunction
Dysuria (painful or difficult urination)
Functional gastrointestinal disorder (functional problem in separate organs of gastrointestinal system)
Hyperphosphataemia (electrolyte disturbance in which there is an abnormally elevated level of phosphate in the blood)
Hypertension (high blood pressure)
Hypoaesthesia (reduced sense of touch or sensation)
Hypocalcaemia (levels of calcium in blood serum are abnormally low)

50-59:

Nephrocalcinosis (a condition in which calcium levels in the kidneys are increased)
Renal failure (kidney dysfunction)
Kidney fibrosis (excess fibrous connective tissue in kidney)
Renal tubular atrophy (wasting of kidney tubules)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
Arteriosclerosis (thickening and hardening of arteries)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Nausea (feeling of having an urge to vomit)
Abdominal pain
Anaemia (lack of blood)

60+:

Fall
Abdominal distension
Depression
Diarrhoea
Escherichia sepsis (bacterial infection by escherichia coli)
Foot fracture
Gastric disorder (disease of stomach)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Humerus fracture (injury to the upper arm bone)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 14.29%
Visual Impairment: 1 person, 7.14%
Pain In Extremity: 1 person, 7.14%
Hypovitaminosis (any of several diseases caused by deficiency of one or more vitamins): 1 person, 7.14%
Hiatal Hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm): 1 person, 7.14%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 1 person, 7.14%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 1 person, 7.14%
Bacterial Infection: 1 person, 7.14%
Back Pain: 1 person, 7.14%
Asthma: 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

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