Otezla and Effient drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Otezla (apremilast) and Effient (prasugrel hydrochloride). Common drug interactions include diarrhoea among females and nausea among males.

The phase IV clinical study analyzes what interactions people have when they take Otezla and Effient. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.

What is Otezla?

Otezla has active ingredients of apremilast. It is often used in psoriatic arthritis. eHealthMe is studying from 146,254 Otezla users. Check the latest studies of Otezla.

What is Effient?

Effient has active ingredients of prasugrel hydrochloride. It is often used in stent. eHealthMe is studying from 9,482 Effient users. Check the latest studies of Effient.

On Jul, 06, 2026

27 people who take Otezla and Effient together, and have interactions are studied.

What are the common drug interactions of Otezla and Effient, by gender? *:

female:

Diarrhoea
Weight decreased
Nausea (feeling of having an urge to vomit)
Decreased appetite
Headache (pain in head)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Psoriasis (immune-mediated disease that affects the skin)
Arthralgia (joint pain)
Hypertension (high blood pressure)
Injection site rash

male:

Nausea (feeling of having an urge to vomit)
Headache (pain in head)
Hyperkalaemia (damage to or disease of the kidney)
Insomnia (sleeplessness)
Malaise (a feeling of general discomfort or uneasiness)
Pyrexia (fever)
Renal failure (kidney dysfunction)
Vomiting
Psoriasis (immune-mediated disease that affects the skin)
Abdominal discomfort

What are the common drug interactions of Otezla and Effient, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Diarrhoea
Headache (pain in head)
Hypertension (high blood pressure)
Nausea (feeling of having an urge to vomit)
Psoriatic arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop)

50-59:

Arthralgia (joint pain)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Abdominal discomfort
Abdominal pain upper
Anxiety
Depression
Dry eye (lack of adequate tears)
Dysgeusia (disorder of the sense of taste)
Dysphonia (speech disorder attributable to a disorder of phonation)
Eructation (release of gas from the digestive tract)

60+:

Nausea (feeling of having an urge to vomit)
Diarrhoea
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Nail disorder (disease of nail)
Arthralgia (joint pain)
Dyspepsia (indigestion)
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Gait disturbance
Heart rate increased

What are the existing conditions these people have? *

Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 13 people, 48.15%
Psoriasis (immune-mediated disease that affects the skin): 12 people, 44.44%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 4 people, 14.81%

* Approximation only. Some reports may have incomplete information.

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