Ovcon-35 and Singulair drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ovcon-35 (ethinyl estradiol; norethindrone) and Singulair (montelukast sodium). Common drug interactions include nausea among females.

The phase IV clinical study analyzes what interactions people have when they take Ovcon-35 and Singulair. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Ovcon-35?

Ovcon-35 has active ingredients of ethinyl estradiol; norethindrone. It is often used in birth control. eHealthMe is studying from 378 Ovcon-35 users. Check the latest studies of Ovcon-35.

What is Singulair?

Singulair has active ingredients of montelukast sodium. It is often used in asthma. eHealthMe is studying from 129,752 Singulair users. Check the latest studies of Singulair.



On Jul, 08, 2026

20 people who take Ovcon-35 and Singulair together, and have interactions are studied.

Ovcon-35 and Singulair drug interactions.

What are the common drug interactions of Ovcon-35 and Singulair, by gender? *:

female:

  1. Nausea (feeling of having an urge to vomit)
  2. Vomiting
  3. Weight increased
  4. Abdominal pain
  5. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  6. Menstruation irregular
  7. Pelvic pain
  8. Depression
  9. Disturbance in attention
  10. Anxiety

male:

n/a

What are the common drug interactions of Ovcon-35 and Singulair, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Blood immunoglobulin g decreased
  2. Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection)
  3. Nausea (feeling of having an urge to vomit)
  4. Pyrexia (fever)
  5. Sinusitis (inflammation of sinus)
  6. Vomiting

20-29:

  1. Abdominal discomfort
  2. Abdominal pain
  3. Abdominal pain upper
  4. Abdominal tenderness
  5. Biliary dyskinesia (motility disorder that affects the gallbladder and sphincter of oddi)
  6. Cholecystitis chronic (long lasting infection of gallbladder)
  7. Epigastric discomfort
  8. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  9. Menstruation irregular
  10. Nausea (feeling of having an urge to vomit)

30-39:

  1. Abdominal pain
  2. Loss of consciousness
  3. Nausea (feeling of having an urge to vomit)
  4. Back pain
  5. Cholecystitis (infection of gallbladder)
  6. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  7. Decreased appetite
  8. Emotional distress
  9. Gastrointestinal disorder (functional problems of gastrointestinal tract)
  10. Gastrointestinal disorder postoperative (functional problems of gastrointestinal tract after surgery)

40-49:

  1. Retinal haemorrhage (bleeding from retina)

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

  1. Premenstrual Syndrome: 8 people, 40.00%
  2. Acne (skin problems that cause pimples): 6 people, 30.00%
  3. Herpes Simplex (herpes simplex is a common viral infection): 6 people, 30.00%
  4. Acne Cystic (skin problems that cause pimples): 6 people, 30.00%
  5. Polycystic Ovary Disease (cysts in the ovaries that occurs when the follicle stops developing): 6 people, 30.00%
  6. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 20.00%
  7. Restless Leg Syndrome (a powerful urge to move your legs): 3 people, 15.00%
  8. Pain: 3 people, 15.00%
  9. Depression: 3 people, 15.00%
  10. Cough: 2 people, 10.00%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Ovcon-35 and Singulair:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ovcon-35:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Singulair:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ovcon-35 and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Singulair and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on ethinyl estradiol; norethindrone and montelukast sodium (the active ingredients of Ovcon-35 and Singulair, respectively), and Ovcon-35 and Singulair (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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