Oxaliplatin and Cipro drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Oxaliplatin (oxaliplatin) and Cipro (ciprofloxacin hydrochloride). Common drug interactions include septic shock among females and dehydration among males.
The phase IV clinical study analyzes what interactions people have when they take Oxaliplatin and Cipro. It is created by eHealthMe based on reports of 54 people who take the same drugs from the FDA, and is updated regularly.
What is Oxaliplatin?
Oxaliplatin has active ingredients of oxaliplatin. It is often used in colon cancer. eHealthMe is studying from 72,058 Oxaliplatin users. Check the latest studies of Oxaliplatin.
What is Cipro?
Cipro has active ingredients of ciprofloxacin hydrochloride. It is often used in urinary tract infection. eHealthMe is studying from 35,126 Cipro users. Check the latest studies of Cipro.
54 people who take Oxaliplatin and Cipro together, and have interactions are studied.

What are the common drug interactions of Oxaliplatin and Cipro, by gender? *:
female:
- Septic shock (shock due to blood infection)
- Somnolence (a state of near-sleep, a strong desire for sleep)
- Corneal perforation (small hole in a cornea)
- Haemolysis (breaking open of red blood cells and the release of haemoglobin into the surrounding fluid)
- Ill-defined disorder
- Oropharyngeal pain
- Pneumonia
- Respiratory arrest (cessation of normal respiration due to failure of the lungs to function effectively)
- Abdominal discomfort
- Abdominal tenderness
male:
- Dehydration (dryness resulting from the removal of water)
- Pyrexia (fever)
- Anaemia (lack of blood)
- Fatigue (feeling of tiredness)
- Febrile neutropenia (fever with reduced white blood cells)
- Hepatic failure (liver failure)
- Intestinal ischaemia (decreased supply of oxygenated blood to the intestines)
- Malignant neoplasm progression (cancer tumour came back)
- Septic shock (shock due to blood infection)
- Syncope (loss of consciousness with an inability to maintain postural tone)
What are the common drug interactions of Oxaliplatin and Cipro, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Alanine aminotransferase increased
- Hepatocellular injury (liver injury)
40-49:
- Large intestine perforation (hole in large intestine)
50-59:
- Anaemia (lack of blood)
- Benign hepatic neoplasm (benign (non-cancerous) tumours of the liver)
- Blood pressure decreased
- Bone pain
- Cholecystitis (infection of gallbladder)
- Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
- Clostridium test positive
- Constipation
- Discomfort
- Disease progression
60+:
- Diarrhoea
- Pyrexia (fever)
- Intestinal ischaemia (decreased supply of oxygenated blood to the intestines)
- Mucosal inflammation (infection of mucous membrane)
- Oesophagitis (inflammation of oesophagus)
- Pain in extremity
- Urinary retention (the inability to completely or partially empty the bladder)
- Abnormal faeces (abnormal stool)
- Benign prostatic hyperplasia (benign enlargement of the prostate)
- Decreased appetite
What are the existing conditions these people have? *
- Nausea (feeling of having an urge to vomit): 12 people, 22.22%
- High Blood Pressure: 9 people, 16.67%
- Constipation: 8 people, 14.81%
- Pain: 8 people, 14.81%
- Infection: 7 people, 12.96%
- Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 7 people, 12.96%
- Rectal Cancer (cancer of rectum): 6 people, 11.11%
- Diarrhea: 6 people, 11.11%
- Hyperlipidaemia (presence of excess lipids in the blood): 5 people, 9.26%
- Insomnia (sleeplessness): 4 people, 7.41%
* Approximation only. Some reports may have incomplete information.
Do you take Oxaliplatin and Cipro?
- Personalize this study to your gender, age, symptoms and drugs
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Oxaliplatin (72,058 reports)
- Cipro (35,126 reports)
Browse all drug interactions of Oxaliplatin and Cipro:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Oxaliplatin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Cipro:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Oxaliplatin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Cipro and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Kim HJ, An SH, Cho YH, Kim SY, Lee HG, Yoon SY, "Oxaliplatin-induced Torsades de pointes and long QT syndrome in a patient with gastric cancer", Acta Oncologica, 2013 Aug .
- Wang JH, King TM, Chang MC, Hsu CW, "Oxaliplatin-induced severe anaphylactic reactions in metastatic colorectal cancer: case series analysis", World journal of gastroenterology: WJG, 2012 Oct .
- Kim HJ, An SH, Cho YH, Kim SY, Lee HG, Yoon SY, "Oxaliplatin-induced Torsades de pointes and long QT syndrome in a patient with gastric cancer", Acta Oncologica, 2013 Aug .
- Wang JH, King TM, Chang MC, Hsu CW, "Oxaliplatin-induced severe anaphylactic reactions in metastatic colorectal cancer: case series analysis", World journal of gastroenterology: WJG, 2012 Oct .
How the study uses the data?
The study uses data from the FDA. It is based on oxaliplatin and ciprofloxacin hydrochloride (the active ingredients of Oxaliplatin and Cipro, respectively), and Oxaliplatin and Cipro (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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