Oxaliplatin and Dulcolax drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Oxaliplatin (oxaliplatin) and Dulcolax (bisacodyl). Common drug interactions include parapsoriasis among females and vomiting among males.

The phase IV clinical study analyzes what interactions people have when they take Oxaliplatin and Dulcolax. It is created by eHealthMe based on reports of 57 people who take the same drugs from the FDA, and is updated regularly.

What is Oxaliplatin?

Oxaliplatin has active ingredients of oxaliplatin. It is often used in colon cancer. eHealthMe is studying from 72,058 Oxaliplatin users. Check the latest studies of Oxaliplatin.

What is Dulcolax?

Dulcolax has active ingredients of bisacodyl. It is often used in constipation. eHealthMe is studying from 12,897 Dulcolax users. Check the latest studies of Dulcolax.



On Jul, 09, 2026

57 people who take Oxaliplatin and Dulcolax together, and have interactions are studied.

Oxaliplatin and Dulcolax drug interactions.

What are the common drug interactions of Oxaliplatin and Dulcolax, by gender? *:

female:

  1. Parapsoriasis (chronic dermatosis of unknown origin, with erythematous , papular, and scaling lesions appearing in)
  2. Pleural effusion (water on the lungs)
  3. Productive cough
  4. Pyrexia (fever)
  5. Respiratory distress (difficulty in breathing)
  6. Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)
  7. Tobacco abuse
  8. Vision blurred
  9. Wheezing (a high-pitched whistling sound made while you breath)
  10. Wound dehiscence (a surgical incision reopens either internally or externally)

male:

  1. Vomiting
  2. Abdominal pain
  3. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  4. Dyspnoea (difficult or laboured respiration)
  5. Embolism (obstruction of an artery, typically by a clot of blood or an air bubble)
  6. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  7. Hypophagia (reduced food intake)
  8. Infection
  9. Leukocytosis (increased white blood cells)
  10. Pulmonary embolism (blockage of the main artery of the lung)

What are the common drug interactions of Oxaliplatin and Dulcolax, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Diarrhoea
  2. Dizziness
  3. Dysgeusia (disorder of the sense of taste)
  4. Vomiting

20-29:

n/a

30-39:

  1. Fatigue (feeling of tiredness)
  2. Headache (pain in head)
  3. Nausea (feeling of having an urge to vomit)
  4. Abdominal pain
  5. Acute respiratory failure
  6. Anaemia of malignant disease
  7. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  8. Anxiety
  9. Asthenia (weakness)
  10. Atelectasis (partial or complete collapse of the lung)

40-49:

  1. Metastatic neoplasm (spreadable cancer tumour)
  2. Pancreatic carcinoma (pancreatic cancer)
  3. Weight decreased
  4. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  5. Death
  6. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  7. Metastases to liver (cancer spreads to liver)
  8. Metastases to lung (cancer spreads to lung)

50-59:

  1. Abdominal pain
  2. Nausea (feeling of having an urge to vomit)
  3. Vomiting
  4. Decreased appetite
  5. Dehydration (dryness resulting from the removal of water)
  6. Fatigue (feeling of tiredness)
  7. Hypotension (abnormally low blood pressure)
  8. Ileus (a painful obstruction of the ileum or other part of the intestine)
  9. Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
  10. Respiratory failure (inadequate gas exchange by the respiratory system)

60+:

  1. Hypertension (high blood pressure)
  2. Muscular weakness (muscle weakness)
  3. Circulatory collapse
  4. Pancreatic carcinoma (pancreatic cancer)
  5. Vomiting
  6. Delirium (wild excitement)
  7. Fatigue (feeling of tiredness)
  8. Neutropenia (an abnormally low number of neutrophils)
  9. Oedema peripheral (superficial swelling)
  10. Pneumonia

What are the existing conditions these people have? *

  1. Pain: 13 people, 22.81%
  2. Nausea (feeling of having an urge to vomit): 11 people, 19.30%
  3. Indigestion: 9 people, 15.79%
  4. Colorectal Cancer Metastatic (cancer of colon and rectal spreads to other parts): 7 people, 12.28%
  5. Diabetes: 7 people, 12.28%
  6. Diarrhea: 7 people, 12.28%
  7. Pancreatic Carcinoma (pancreatic cancer): 6 people, 10.53%
  8. Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 6 people, 10.53%
  9. High Blood Pressure: 6 people, 10.53%
  10. Haemorrhoids (a swollen vein or group of veins in the region of the anus): 5 people, 8.77%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Oxaliplatin and Dulcolax:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Oxaliplatin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Dulcolax:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Oxaliplatin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Dulcolax and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on oxaliplatin and bisacodyl (the active ingredients of Oxaliplatin and Dulcolax, respectively), and Oxaliplatin and Dulcolax (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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