Oxaprozin and Metaxalone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Oxaprozin (oxaprozin) and Metaxalone (metaxalone). Common drug interactions include tonsillitis among females and dysarthria among males.

The phase IV clinical study analyzes what interactions people have when they take Oxaprozin and Metaxalone. It is created by eHealthMe based on reports of 30 people who take the same drugs from the FDA, and is updated regularly.

What is Oxaprozin?

Oxaprozin has active ingredients of oxaprozin. It is often used in joint pain. eHealthMe is studying from 1,578 Oxaprozin users. Check the latest studies of Oxaprozin.

What is Metaxalone?

Metaxalone has active ingredients of metaxalone. It is often used in back pain. eHealthMe is studying from 4,452 Metaxalone users. Check the latest studies of Metaxalone.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 25, 2026

30 people who take Oxaprozin and Metaxalone together, and have interactions are studied.

Oxaprozin and Metaxalone drug interactions.

What are the common drug interactions of Oxaprozin and Metaxalone, by gender? *:

female:

Tonsillitis (inflammation of tonsil)
Vision blurred
Visual disturbance
Gait disturbance
Fall
Pain in extremity
Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
Limb discomfort (discomfort in leg)
Malaise (a feeling of general discomfort or uneasiness)
Mobility decreased (ability to move is reduced)

male:

Dysarthria (speech disorder)
Weakness
Bone pain
Chest pain
Confusion
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Erythema (redness of the skin)
Fall
Flushing (the warm, red condition of human skin)
Gastroenteritis helicobacter (inflammation of stomach and intestine caused by helicobacter infection)

What are the common drug interactions of Oxaprozin and Metaxalone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Disturbance in attention
Gastrointestinal pain
Headache (pain in head)
Memory impairment
Nausea (feeling of having an urge to vomit)
Vomiting
Weight decreased

40-49:

Fall
Blood triglycerides increased
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Gait disturbance
Hepatocellular damage (liver damage)
Loss of consciousness
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Anxiety
Arthropathy
Blood cholesterol increased

50-59:

Asthenia (weakness)
Gait disturbance
Limb discomfort (discomfort in leg)
Nasopharyngitis (inflammation of the nasopharynx)
Pain in extremity
Vomiting

60+:

Chronic kidney disease
Dry eye (lack of adequate tears)
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 12 people, 40.00%
High Blood Cholesterol: 4 people, 13.33%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 10.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 10.00%
Panic Disorder: 2 people, 6.67%
Pain: 2 people, 6.67%
Intervertebral Disc Protrusion (spinal disc protrusion): 2 people, 6.67%
Gait Disturbance: 2 people, 6.67%
Fluid Retention (an abnormal accumulation of fluid in the blood): 2 people, 6.67%
Bipolar Disorder (mood disorder): 2 people, 6.67%

* Approximation only. Some reports may have incomplete information.

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