Oxbryta and Lactulose drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Oxbryta (voxelotor) and Lactulose (lactulose). Common drug interactions include abdominal discomfort among females and atelectasis among males.

The phase IV clinical study analyzes what interactions people have when they take Oxbryta and Lactulose. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Oxbryta?

Oxbryta has active ingredients of voxelotor. eHealthMe is studying from 24,969 Oxbryta users. Check the latest studies of Oxbryta.

What is Lactulose?

Lactulose has active ingredients of lactulose. It is often used in constipation. eHealthMe is studying from 46,960 Lactulose users. Check the latest studies of Lactulose.

On Aug, 04, 2026

16 people who take Oxbryta and Lactulose together, and have interactions are studied.

Oxbryta and Lactulose drug interactions.

What are the common drug interactions of Oxbryta and Lactulose, by gender? *:

female:

Abdominal discomfort
Abdominal pain upper
Fatigue (feeling of tiredness)
Hepatic enzyme increased
Headache (pain in head)
Abdominal pain
Alopecia (absence of hair from areas of the body)
Diarrhoea
Migraine (headache)

male:

Atelectasis (partial or complete collapse of the lung)
Musculoskeletal chest pain (pain in chest muscle or nerve or bones)
Blood lactate dehydrogenase increased
Haemorrhagic stroke (stroke caused by the rupture of a blood vessel in the brain)
Platelet count decreased
Pain
Pulmonary embolism (blockage of the main artery of the lung)
Thrombocytosis
Stress
Bilirubin conjugated increased

What are the common drug interactions of Oxbryta and Lactulose, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Stress

20-29:

Headache (pain in head)
Thrombocytosis
Bilirubin conjugated increased
Blood alkaline phosphatase increased
Blood bilirubin increased
Blood creatinine decreased
Blood lactate dehydrogenase increased
Platelet count decreased

30-39:

Atelectasis (partial or complete collapse of the lung)
Musculoskeletal chest pain (pain in chest muscle or nerve or bones)
Pain
Pulmonary embolism (blockage of the main artery of the lung)
Alopecia (absence of hair from areas of the body)

40-49:

n/a

50-59:

n/a

60+:

Abdominal discomfort
Abdominal pain upper
Fatigue (feeling of tiredness)
Hepatic enzyme increased
Haemorrhagic stroke (stroke caused by the rupture of a blood vessel in the brain)

What are the existing conditions these people have? *

Pain: 2 people, 12.50%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 12.50%
Hyperchlorhydria (gastric acid levels are higher in stomach): 2 people, 12.50%
Gastric Ulcer (stomach ulcer): 2 people, 12.50%
Headache (pain in head): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

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