Oxycodone and acetaminophen and Cisplatin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Oxycodone and acetaminophen (acetaminophen; oxycodone hydrochloride) and Cisplatin (cisplatin). Common drug interactions include body temperature increased among females and anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Oxycodone and acetaminophen and Cisplatin. It is created by eHealthMe based on reports of 42 people who take the same drugs from the FDA, and is updated regularly.

What is Oxycodone and acetaminophen?

Oxycodone and acetaminophen has active ingredients of acetaminophen; oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 14,467 Oxycodone and acetaminophen users. Check the latest studies of Oxycodone and acetaminophen.

What is Cisplatin?

Cisplatin has active ingredients of cisplatin. It is often used in chemotherapy. eHealthMe is studying from 92,837 Cisplatin users. Check the latest studies of Cisplatin.

On Aug, 01, 2026

42 people who take Oxycodone and acetaminophen and Cisplatin together, and have interactions are studied.

Oxycodone and acetaminophen and Cisplatin drug interactions.

What are the common drug interactions of Oxycodone And Acetaminophen and Cisplatin, by gender? *:

female:

Body temperature increased
Cardiac arrest
Cardiomyopathy (weakening of the heart muscle)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Dyspnoea (difficult or laboured respiration)
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Gastrointestinal necrosis (destruction of gastrointestinal organ)
Gastrointestinal oedema (excessive build-up of fluid in the gastrointestinal tract tissues)
Hypotension (abnormally low blood pressure)
Induration (thickening of tissue)

male:

Anaemia (lack of blood)
Platelet count decreased
Hypovolaemia (a decreased volume of circulating blood in the body)
Loss of consciousness
Lymphadenopathy (disease or enlargement of lymph nodes)
Muscular weakness (muscle weakness)
Pulmonary oedema (fluid accumulation in the lungs)
Pyrexia (fever)
Renal failure acute (rapid kidney dysfunction)
Tremor (trembling or shaking movements in one or more parts of your body)

What are the common drug interactions of Oxycodone And Acetaminophen and Cisplatin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Neuralgia (pain in one or more nerves)
Neuropathy peripheral (surface nerve damage)
Respiratory depression (respiration has a rate below 12 breaths)
Sedation
Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)
Death
Confusional state
Constipation
Diarrhoea
Drug ineffective

50-59:

Anaemia (lack of blood)
Platelet count decreased
Cellulitis (infection under the skin)
Dehydration (dryness resulting from the removal of water)
Pulmonary embolism (blockage of the main artery of the lung)
Pyrexia (fever)
Thrombophlebitis deep (deep swelling (inflammation) of a vein caused by a blood clot)
Urinary tract infection
Chronic gastritis (long lasting infection of stomach lining)
Cardiac arrest

60+:

Agitation (state of anxiety or nervous excitement)
Anaemia (lack of blood)
Febrile neutropenia (fever with reduced white blood cells)
Hypovolaemia (a decreased volume of circulating blood in the body)
Loss of consciousness
Lymphadenopathy (disease or enlargement of lymph nodes)
Muscular weakness (muscle weakness)
Pulmonary oedema (fluid accumulation in the lungs)
Pyrexia (fever)
Renal failure acute (rapid kidney dysfunction)

What are the existing conditions these people have? *

Constipation: 11 people, 26.19%
White Blood Cell Count Decreased: 9 people, 21.43%
Fever: 8 people, 19.05%
High Blood Pressure: 6 people, 14.29%
Nausea And Vomiting: 5 people, 11.90%
Nausea (feeling of having an urge to vomit): 5 people, 11.90%
Ph Urine Increased: 5 people, 11.90%
Conjunctivitis (pink eye): 5 people, 11.90%
Blood Uric Acid Decreased: 5 people, 11.90%
Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 4 people, 9.52%

* Approximation only. Some reports may have incomplete information.

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