Oxycodone hydrochloride and Levoxyl drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Oxycodone hydrochloride (oxycodone hydrochloride) and Levoxyl (levothyroxine sodium). Common drug interactions include fall among females and arthralgia among males.

The phase IV clinical study analyzes what interactions people have when they take Oxycodone hydrochloride and Levoxyl. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Oxycodone hydrochloride?

Oxycodone hydrochloride has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 36,817 Oxycodone hydrochloride users. Check the latest studies of Oxycodone hydrochloride.

What is Levoxyl?

Levoxyl has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. eHealthMe is studying from 25,178 Levoxyl users. Check the latest studies of Levoxyl.



On Jul, 10, 2026

22 people who take Oxycodone hydrochloride and Levoxyl together, and have interactions are studied.

Oxycodone hydrochloride and Levoxyl drug interactions.

What are the common drug interactions of Oxycodone Hydrochloride and Levoxyl, by gender? *:

female:

  1. Fall
  2. Fatigue (feeling of tiredness)
  3. Gastrointestinal infection (infection of stomach and intestine)
  4. Infusion related reaction
  5. Joint swelling
  6. Pain in extremity
  7. Pneumonia
  8. Retinal pigmentation (pigmentation of retina)
  9. Urinary tract infection
  10. Wrist fracture

male:

  1. Arthralgia (joint pain)
  2. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  3. Finger deformity (a deformed position of the finger)
  4. Foot deformity (functional disability of foot)
  5. Gastric disorder (disease of stomach)
  6. General physical health deterioration (weak health status)
  7. Hepatic enzyme increased
  8. Hip arthroplasty
  9. Hyperbilirubinaemia (excess of bilirubin in the blood)
  10. Hypercholesterolaemia (high levels of cholesterol in the blood)

What are the common drug interactions of Oxycodone Hydrochloride and Levoxyl, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Ascites (accumulation of fluid in the abdominal cavity)
  2. Fall
  3. General physical health deterioration (weak health status)
  4. Hyperbilirubinaemia (excess of bilirubin in the blood)
  5. Blood potassium decreased
  6. Dehydration (dryness resulting from the removal of water)
  7. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
  8. Drug hypersensitivity

60+:

  1. Mitral valve incompetence (inefficient heart valve)
  2. Retinal pigmentation (pigmentation of retina)
  3. Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries)
  4. Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
  5. Cardiomyopathy (weakening of the heart muscle)
  6. Carotid artery disease
  7. Central nervous system lesion (an abnormality in tissue of brain or spinal cord)
  8. Chest discomfort
  9. Decreased appetite
  10. Device related infection

What are the existing conditions these people have? *

  1. Immunodeficiency Common Variable: 8 people, 36.36%
  2. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 5 people, 22.73%
  3. Primary Immunodeficiency Syndrome: 4 people, 18.18%
  4. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 13.64%
  5. Thyroid Diseases: 2 people, 9.09%
  6. Neuralgia (pain in one or more nerves): 2 people, 9.09%
  7. Mixed Connective Tissue Disease (an autoimmune disease, in which the body's defence system attacks itself): 2 people, 9.09%
  8. Migraine (headache): 2 people, 9.09%
  9. Indigestion: 2 people, 9.09%
  10. Immunodeficiency: 2 people, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Oxycodone hydrochloride and Levoxyl?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Oxycodone hydrochloride and Levoxyl:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Oxycodone hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Levoxyl:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Oxycodone hydrochloride and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Levoxyl and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on oxycodone hydrochloride and levothyroxine sodium (the active ingredients of Oxycodone hydrochloride and Levoxyl, respectively), and Oxycodone hydrochloride and Levoxyl (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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