Oxycodone hydrochloride and Lopressor drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Oxycodone hydrochloride (oxycodone hydrochloride) and Lopressor (metoprolol tartrate). Common drug interactions include gastritis among females and constipation among males.

The phase IV clinical study analyzes what interactions people have when they take Oxycodone hydrochloride and Lopressor. It is created by eHealthMe based on reports of 25 people who take the same drugs from the FDA, and is updated regularly.

What is Oxycodone hydrochloride?

Oxycodone hydrochloride has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 36,817 Oxycodone hydrochloride users. Check the latest studies of Oxycodone hydrochloride.

What is Lopressor?

Lopressor has active ingredients of metoprolol tartrate. It is often used in high blood pressure. eHealthMe is studying from 33,152 Lopressor users. Check the latest studies of Lopressor.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

25 people who take Oxycodone hydrochloride and Lopressor together, and have interactions are studied.

Oxycodone hydrochloride and Lopressor drug interactions.

What are the common drug interactions of Oxycodone Hydrochloride and Lopressor, by gender? *:

female:

Gastritis (inflammation of stomach)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Gingivitis (inflammation of gums)
Glaucoma (increased fluid pressure in the eye with vision loss)
Haematochezia (passage of stools containing blood)
Haemorrhoids (a swollen vein or group of veins in the region of the anus)
Head injury
Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
Histoplasmosis (infection caused by breathing in spores of a fungus)

male:

Constipation
Dizziness
Aggression
Cellulitis (infection under the skin)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Cough
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Diarrhoea
Dry mouth
Dysphonia (speech disorder attributable to a disorder of phonation)

What are the common drug interactions of Oxycodone Hydrochloride and Lopressor, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Gingivitis (inflammation of gums)
Glaucoma (increased fluid pressure in the eye with vision loss)
Haematochezia (passage of stools containing blood)
Haemorrhoids (a swollen vein or group of veins in the region of the anus)
Head injury
Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
Histoplasmosis (infection caused by breathing in spores of a fungus)
Hypoaesthesia (reduced sense of touch or sensation)

30-39:

n/a

40-49:

n/a

50-59:

Anaemia (lack of blood)
Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
Ewing's sarcoma (malignant small, round, blue cell tumour)
Peripheral swelling

60+:

Nausea (feeling of having an urge to vomit)
Constipation
Neuropathy peripheral (surface nerve damage)
Neurotoxicity (when the exposure to natural or artificial toxic substances, which are called neurotoxins, alters the normal activity of the nervous system)
Pneumonia
Skin cancer
White blood cell count decreased
Aggression
Asthenia (weakness)
Blood creatinine increased

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 9 people, 36.00%
Renal Cell Carcinoma (a kidney cancer): 3 people, 12.00%
Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 2 people, 8.00%

* Approximation only. Some reports may have incomplete information.

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