Oxycodone hydrochloride and Primidone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Oxycodone hydrochloride (oxycodone hydrochloride) and Primidone (primidone). Common drug interactions include abdominal hernia among females and cardiac disorder among males.

The phase IV clinical study analyzes what interactions people have when they take Oxycodone hydrochloride and Primidone. It is created by eHealthMe based on reports of 25 people who take the same drugs from the FDA, and is updated regularly.

What is Oxycodone hydrochloride?

Oxycodone hydrochloride has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 36,817 Oxycodone hydrochloride users. Check the latest studies of Oxycodone hydrochloride.

What is Primidone?

Primidone has active ingredients of primidone. It is often used in essential tremor. eHealthMe is studying from 10,474 Primidone users. Check the latest studies of Primidone.

On Jul, 11, 2026

25 people who take Oxycodone hydrochloride and Primidone together, and have interactions are studied.

Oxycodone hydrochloride and Primidone drug interactions.

What are the common drug interactions of Oxycodone Hydrochloride and Primidone, by gender? *:

female:

Abdominal hernia
Abdominal pain upper
Cellulitis (infection under the skin)
Drug level decreased
Dyspnoea (difficult or laboured respiration)
Ear haemorrhage (bleeding from ear)
Eye pruritus (eye itching)
Fatigue (feeling of tiredness)
Hypoxia (low oxygen in tissues)
Infection

male:

Cardiac disorder
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Drug abuse
Drug dependence
Ejection fraction decreased (systolic heart failure)
Hypoacusis (loss of hearing)
Surgery

What are the common drug interactions of Oxycodone Hydrochloride and Primidone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Constipation
Haemorrhoids (a swollen vein or group of veins in the region of the anus)
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Muscle spasticity (tight or stiff muscles and an inability to control those muscles)

60+:

Pneumonia
Abdominal hernia
Infection
Infusion site pain
Infusion site pruritus (severe itching at infusion site)
Infusion site swelling
Localised infection (infection at the single location)
Lymphoedema (localized fluid retention and tissue swelling)
Pericardial effusion (fluid around the heart)
Peripheral swelling

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 6 people, 24.00%
Primary Immunodeficiency Syndrome: 4 people, 16.00%
Immunodeficiency Common Variable: 4 people, 16.00%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 12.00%

* Approximation only. Some reports may have incomplete information.

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