Oxycodone and Cefazolin sodium drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Oxycodone (oxycodone hydrochloride) and Cefazolin sodium (cefazolin sodium). Common drug interactions include renal tubular necrosis among females and confusion postoperative among males.

The phase IV clinical study analyzes what interactions people have when they take Oxycodone and Cefazolin sodium. It is created by eHealthMe based on reports of 91 people who take the same drugs from the FDA, and is updated regularly.

What is Oxycodone?

Oxycodone has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 162,592 Oxycodone users. Check the latest studies of Oxycodone.

What is Cefazolin sodium?

Cefazolin sodium has active ingredients of cefazolin sodium. eHealthMe is studying from 3,649 Cefazolin sodium users. Check the latest studies of Cefazolin sodium.

On Jul, 11, 2026

91 people who take Oxycodone and Cefazolin sodium together, and have interactions are studied.

Oxycodone and Cefazolin sodium drug interactions.

What are the common drug interactions of Oxycodone and Cefazolin Sodium, by gender? *:

female:

Renal tubular necrosis (death of kidney tubules)
Vision blurred
Alanine aminotransferase increased
Burning sensation
Cataract subcapsular (cataracts that affect the back of the lens)
Cystoid macular oedema (fluid accumulation after cataract surgery)
Diabetes mellitus inadequate control
Diabetic retinal oedema (excessive build-up of fluid in the retina due to diabetes)
Diabetic retinopathy (damage to the retina caused by complications of diabetes)
Dizziness

male:

Confusion postoperative
Renal failure (kidney dysfunction)
Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
Erysipelas (bacterial skin infection)
Oxygen saturation decreased
Pruritus (severe itching of the skin)
Serum sickness (hypersensitivity reaction that results from the injection of heterologous or foreign protein or serum)
Vascular purpura (haemorrhages in the skin and mucous membranes that result in the appearance of purplish spots or patches)
Abdominal pain
Adrenal haemorrhage (bleeding into the adrenal gland)

What are the common drug interactions of Oxycodone and Cefazolin Sodium, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Abdominal pain upper
Amenorrhoea (absence of a menstrual period in a woman of reproductive age)
Headache (pain in head)
Human chorionic gonadotropin increased
Nausea (feeling of having an urge to vomit)
Post abortion haemorrhage
Pregnancy
Pregnancy test positive
Uterine haemorrhage (uterine bleeding)
Uterine infection

30-39:

Gamma-glutamyltransferase increased
Chronic kidney disease
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)
Renal tubular acidosis (medical condition that involves an accumulation of acid in the body due to a failure of the kidneys)
Unevaluable reaction

40-49:

Alanine aminotransferase increased
Burning sensation
Cataract subcapsular (cataracts that affect the back of the lens)
Cystoid macular oedema (fluid accumulation after cataract surgery)
Diabetes mellitus inadequate control
Diabetic retinal oedema (excessive build-up of fluid in the retina due to diabetes)
Diabetic retinopathy (damage to the retina caused by complications of diabetes)
Dizziness
Dizziness postural
Episcleritis (acute inflammatory disorder of the episclera of eye)

50-59:

Sepsis (a severe blood infection that can lead to organ failure and death)
Anxiety
Death
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Oedema peripheral (superficial swelling)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Cellulitis (infection under the skin)
Chills (felling of cold)

60+:

Chronic kidney disease
Pyrexia (fever)
Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
Erysipelas (bacterial skin infection)
Oxygen saturation decreased
Pruritus (severe itching of the skin)
Serum sickness (hypersensitivity reaction that results from the injection of heterologous or foreign protein or serum)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Abdominal pain
Activated partial thromboplastin time prolonged

What are the existing conditions these people have? *

High Blood Pressure: 17 people, 18.68%
Anaesthesia: 15 people, 16.48%
Depression: 15 people, 16.48%
Nausea (feeling of having an urge to vomit): 15 people, 16.48%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 15 people, 16.48%
Insomnia (sleeplessness): 12 people, 13.19%
Diabetes: 11 people, 12.09%
High Blood Cholesterol: 10 people, 10.99%
Parkinson's Disease: 8 people, 8.79%
Fungal Infection: 8 people, 8.79%

* Approximation only. Some reports may have incomplete information.

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