Oxycodone and Ornithine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Oxycodone (oxycodone hydrochloride) and Ornithine (ornithine). Common drug interactions include cytokine release syndrome among females and pyrexia among males.

The phase IV clinical study analyzes what interactions people have when they take Oxycodone and Ornithine. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Oxycodone?

Oxycodone has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 162,592 Oxycodone users. Check the latest studies of Oxycodone.

What is Ornithine?

Ornithine has active ingredients of ornithine. eHealthMe is studying from 591 Ornithine users. Check the latest studies of Ornithine.



On Jul, 11, 2026

17 people who take Oxycodone and Ornithine together, and have interactions are studied.

Oxycodone and Ornithine drug interactions.

What are the common drug interactions of Oxycodone and Ornithine, by gender? *:

female:

  1. Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
  2. Thrombocytopenia (decrease of platelets in blood)
  3. Blood creatinine increased
  4. Blood pressure decreased
  5. Blood urea increased
  6. Body temperature increased
  7. C-reactive protein increased
  8. Hypercalcaemia (elevated calcium (ca+) level in the blood)
  9. Neutropenia (an abnormally low number of neutrophils)
  10. Sepsis (a severe blood infection that can lead to organ failure and death)

male:

  1. Pyrexia (fever)
  2. Presyncope
  3. General physical health deterioration (weak health status)
  4. Leukopenia (less number of white blood cells in blood)
  5. Malignant neoplasm progression (cancer tumour came back)
  6. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  7. Rhinorrhoea (watery mucus discharge from the nose)
  8. Proctitis (inflammation of the rectum and anus)
  9. Abdominal distension
  10. Abdominal pain

What are the common drug interactions of Oxycodone and Ornithine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Blood pressure decreased
  2. Hepatic failure (liver failure)
  3. Neutropenia (an abnormally low number of neutrophils)
  4. Bone marrow failure
  5. Alanine aminotransferase increased
  6. Aspartate aminotransferase increased
  7. Azotaemia (excess of urea or other nitrogenous compounds in the blood)
  8. Blood urea increased
  9. Body temperature increased
  10. C-reactive protein increased

60+:

  1. Presyncope
  2. Pyrexia (fever)
  3. Sepsis (a severe blood infection that can lead to organ failure and death)
  4. Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
  5. Proctitis (inflammation of the rectum and anus)
  6. Paraparesis (partial paralysis of the lower limbs)

What are the existing conditions these people have? *

  1. Abdominal Pain: 6 people, 35.29%
  2. Constipation: 6 people, 35.29%
  3. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 29.41%
  4. Diabetes: 5 people, 29.41%
  5. Rashes (redness): 5 people, 29.41%
  6. Gastrointestinal Disorder (functional problems of gastrointestinal tract): 4 people, 23.53%
  7. Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 4 people, 23.53%
  8. Diarrhea: 4 people, 23.53%
  9. Enlarged Prostate: 4 people, 23.53%
  10. Fever: 4 people, 23.53%

* Approximation only. Some reports may have incomplete information.

Do you take Oxycodone and Ornithine?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Oxycodone and Ornithine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Oxycodone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Ornithine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Oxycodone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ornithine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on oxycodone hydrochloride and ornithine (the active ingredients of Oxycodone and Ornithine, respectively), and Oxycodone and Ornithine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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