Qinlock and Oxycodone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Qinlock (ripretinib) and Oxycodone (oxycodone hydrochloride). Common drug interactions include dry skin among females and fatigue among males.

The phase IV clinical study analyzes what interactions people have when they take Qinlock and Oxycodone. It is created by eHealthMe based on reports of 37 people who take the same drugs from the FDA, and is updated regularly.

What is Qinlock?

Qinlock has active ingredients of ripretinib. eHealthMe is studying from 3,803 Qinlock users. Check the latest studies of Qinlock.

What is Oxycodone?

Oxycodone has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 162,588 Oxycodone users. Check the latest studies of Oxycodone.



On Dec, 19, 2025

37 people who take Qinlock and Oxycodone together, and have interactions are studied.

Qinlock and Oxycodone drug interactions.

What are the common drug interactions of Qinlock and Oxycodone, by gender? *:

female:

  1. Dry skin
  2. Dyspnoea (difficult or laboured respiration)
  3. Hepatic enzyme increased
  4. Melanocytic naevus (a type of lesion that contains nevus cells (a type of melanocyte))
  5. Palmar-plantar erythrodysaesthesia syndrome (hand-foot syndrome)
  6. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  7. Productive cough
  8. Rash
  9. Red blood cell count decreased
  10. Skin exfoliation (removal of the oldest dead skin cells)

male:

  1. Fatigue (feeling of tiredness)
  2. Constipation
  3. Pruritus (severe itching of the skin)
  4. Weight decreased
  5. Appetite disorder (abnormal eating habits)
  6. Blood glucose decreased
  7. Decreased appetite
  8. Dry skin
  9. Insomnia (sleeplessness)
  10. Joint swelling

What are the common drug interactions of Qinlock and Oxycodone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Abdominal pain
  2. Decreased appetite
  3. Dehydration (dryness resulting from the removal of water)
  4. Fatigue (feeling of tiredness)
  5. Hepatic enzyme increased

20-29:

n/a

30-39:

  1. Dry skin
  2. Dyspnoea (difficult or laboured respiration)
  3. Melanocytic naevus (a type of lesion that contains nevus cells (a type of melanocyte))
  4. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  5. Productive cough
  6. Skin exfoliation (removal of the oldest dead skin cells)

40-49:

n/a

50-59:

  1. Fatigue (feeling of tiredness)
  2. Abdominal pain
  3. Anaemia (lack of blood)
  4. Anxiety
  5. Arthralgia (joint pain)
  6. Bone pain
  7. Cellulitis (infection under the skin)
  8. Constipation
  9. Dizziness
  10. Dry skin

60+:

  1. Nausea (feeling of having an urge to vomit)
  2. Fatigue (feeling of tiredness)
  3. Alopecia (absence of hair from areas of the body)
  4. Constipation
  5. Neoplasm progression (growth of tumour)
  6. Abdominal pain
  7. Arthralgia (joint pain)
  8. Decreased appetite
  9. Fall
  10. Headache (pain in head)

What are the existing conditions these people have? *

  1. Gastrointestinal Stromal Tumor: 18 people, 48.65%
  2. Nausea And Vomiting: 2 people, 5.41%
  3. Nausea (feeling of having an urge to vomit): 2 people, 5.41%

* Approximation only. Some reports may have incomplete information.

Do you take Qinlock and Oxycodone?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Qinlock and Oxycodone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Qinlock:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Oxycodone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Qinlock and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Oxycodone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on ripretinib and oxycodone hydrochloride (the active ingredients of Qinlock and Oxycodone, respectively), and Qinlock and Oxycodone (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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