A study for a 72 year old woman who takes Paracetamol, Levothyroxine Thyroid, Tramadol, Ibuprofen (an AI-powered real world drug study)

Summary:

1,766 females aged 72 (±5) who take the same drugs and have adverse effects are studied. This is a phase IV clinical study for a 72 year old female patient who has Adult Hypothyroidism, Insomnia, Sciatica Aggravated. The study is created by eHealthMe based on reports from sources including the FDA.

On Jan, 24, 2026

1,766 females aged 72 (±5) who take Paracetamol, Levothyroxine Thyroid, Tramadol, Ibuprofen and have adverse effects are studied.

Number of reports submitted per year:

Paracetamol, Levothyroxine Thyroid, Tramadol, Ibuprofen for a 72-year old woman.

Information of the patient in this study:

Age: 72
Gender: female

What are the drugs?

Paracetamol has active ingredients of acetaminophen. It is often used in pain. eHealthMe is studying from 115,644 Paracetamol users. Check the latest studies of Paracetamol.
Levothyroxine thyroid has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. eHealthMe is studying from 4,073 Levothyroxine thyroid users. Check the latest studies of Levothyroxine thyroid.
Tramadol has active ingredients of tramadol hydrochloride. It is often used in pain. eHealthMe is studying from 235,787 Tramadol users. Check the latest studies of Tramadol.
Ibuprofen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 245,263 Ibuprofen users. Check the latest studies of Ibuprofen.

What are the conditions?

Adult hypothyroidism (swelling and inflammation damage the thyroid glands cells in adult) is found to be associated with 2,525 drugs and 2,622 conditions by eHealthMe. Check the latest studies of Adult hypothyroidism.
Insomnia (sleeplessness) is found to be associated with 3,119 drugs and 5,144 conditions by eHealthMe. Check the latest studies of Insomnia.
Sciatica aggravated (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve) is found to be associated with 1,062 drugs and 397 conditions by eHealthMe. Check the latest studies of Sciatica aggravated.

Common drug interactions *:

Fatigue (feeling of tiredness): 233 people, 13.19%
Nausea (feeling of having an urge to vomit): 169 people, 9.57%
Diarrhea : 164 people, 9.29%
Fall : 162 people, 9.17%
Chronic Kidney Disease : 143 people, 8.10%
Weakness : 138 people, 7.81%
Joint Pain : 134 people, 7.59%
Dyspnea (difficult or laboured breathing): 131 people, 7.42%
Acute Kidney Failure : 111 people, 6.29%
Dizziness : 106 people, 6.00%
Urinary Tract Infection : 106 people, 6.00%
Pain In Extremity : 103 people, 5.83%
Nausea And Vomiting : 103 people, 5.83%
High Blood Pressure : 95 people, 5.38%
Drug Ineffective : 89 people, 5.04%
Rashes (redness): 88 people, 4.98%
Sinusitis (inflammation of sinus): 87 people, 4.93%
Pneumonia : 87 people, 4.93%
Constipation : 85 people, 4.81%
Malaise (a feeling of general discomfort or uneasiness): 85 people, 4.81%

Common co-existing conditions *:

You may use this to check any potential undetected conditions.

High Blood Pressure : 219 people, 12.40%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 215 people, 12.17%
High Blood Cholesterol : 147 people, 8.32%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 114 people, 6.46%
Multiple Myeloma (cancer of the plasma cells): 103 people, 5.83%
Immunodeficiency Common Variable : 101 people, 5.72%
Nausea (feeling of having an urge to vomit): 98 people, 5.55%
Constipation : 97 people, 5.49%
Stress And Anxiety : 90 people, 5.10%
Joint Pain : 87 people, 4.93%
Depression : 84 people, 4.76%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 69 people, 3.91%
Osteoporosis (bones weak and more likely to break): 64 people, 3.62%
Asthma : 62 people, 3.51%
Infection : 60 people, 3.40%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 52 people, 2.94%
Diabetes : 51 people, 2.89%
Hypersensitivity : 47 people, 2.66%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 41 people, 2.32%
Muscle Spasms (muscle contraction): 41 people, 2.32%

Common co-used drugs *:

You may use this to check any potential interacting drugs.

Drug effectiveness *:

Paracetamol:

n/a

Levothyroxine Thyroid:

n/a

Tramadol:

n/a

Ibuprofen:

n/a

* Some reports may have incomplete information.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Related studies

Drug side effects in long term, by gender and age:

Ibuprofen: 245,263 reports
Levothyroxine thyroid: 4,073 reports
Paracetamol: 115,644 reports
Tramadol: 235,787 reports

Treatments, associated medications and conditions:

Adult hypothyroidism: 168,034 reports
Insomnia: 438,025 reports
Sciatica aggravated: 116 reports

Drug interactions:

How the phase IV clinical study uses the data?

The study is based on gender, age, active ingredients of any drugs used. Other drugs that have the same active ingredients (e.g. generic drugs) are considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.