Oxycodone and Sulfatrim drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Oxycodone (oxycodone hydrochloride) and Sulfatrim (sulfamethoxazole; trimethoprim). Common drug interactions include pyrexia among females and heart rate decreased among males.

The phase IV clinical study analyzes what interactions people have when they take Oxycodone and Sulfatrim. It is created by eHealthMe based on reports of 85 people who take the same drugs from the FDA, and is updated regularly.

What is Oxycodone?

Oxycodone has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 162,592 Oxycodone users. Check the latest studies of Oxycodone.

What is Sulfatrim?

Sulfatrim has active ingredients of sulfamethoxazole; trimethoprim. eHealthMe is studying from 4,140 Sulfatrim users. Check the latest studies of Sulfatrim.

On Aug, 07, 2026

85 people who take Oxycodone and Sulfatrim together, and have interactions are studied.

Oxycodone and Sulfatrim drug interactions.

What are the common drug interactions of Oxycodone and Sulfatrim, by gender? *:

female:

Pyrexia (fever)
Wound
Arthralgia (joint pain)
Asthenia (weakness)
Blood pressure decreased
Body temperature increased
Diarrhoea
Fall
Impaired gastric emptying
Influenza

male:

Heart rate decreased
Nasopharyngitis (inflammation of the nasopharynx)
Bone pain
Calculus bladder (bladder stone)
Cellulitis (infection under the skin)
Chest pain
Confusional state
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Ear infection
Ear pain

What are the common drug interactions of Oxycodone and Sulfatrim, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Abdominal discomfort
Bell's palsy (facial paralysis)
Blindness
Constipation
Decreased appetite
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Hypersomnia (excessive daytime sleepiness (eds))
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Malignant ascites (a condition in which a person with cancer has an accumulation of fluid in the abdomen)
Malignant neoplasm progression (cancer tumour came back)

20-29:

Abdominal pain lower
Arrhythmia (irregular heartbeat)
Arthralgia (joint pain)
Arthropathy
Asthenia (weakness)
Autonomic nervous system imbalance (autonomic nervous system is of net equal emphasis)
Blood cholinesterase increased
Blood creatinine increased
Blood disorder
Blood pressure decreased

30-39:

n/a

40-49:

Abdominal distension
Abdominal pain
Abdominal pain upper
Anal abscess
Constipation
Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
Drug ineffective
Drug level decreased
Dyspepsia (indigestion)
Dyspnoea (difficult or laboured respiration)

50-59:

Bone pain
Calculus bladder (bladder stone)
Cellulitis (infection under the skin)
Chest pain
Confusional state
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Drug hypersensitivity
Drug ineffective
Ear infection
Ear pain

60+:

Blood pressure systolic increased
Blood pressure diastolic decreased
Blood pressure fluctuation
Dyspnoea (difficult or laboured respiration)
Erythema (redness of the skin)
Influenza
Muscular weakness (muscle weakness)
Nasopharyngitis (inflammation of the nasopharynx)
Oxygen saturation decreased
Pain in extremity

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 32 people, 37.65%
Polychondritis (progressive inflammation of cartilage and other connective tissue): 13 people, 15.29%
High Blood Pressure: 7 people, 8.24%
Vasculitis Necrotising (inflammation and damage to blood vessels): 6 people, 7.06%
Stress And Anxiety: 5 people, 5.88%
High Blood Cholesterol: 5 people, 5.88%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 5.88%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 5 people, 5.88%
Anti-Cyclic Citrullinated Peptide Antibody Positive: 5 people, 5.88%

* Approximation only. Some reports may have incomplete information.

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