Oxycontin and Braftovi drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Oxycontin (oxycodone hydrochloride) and Braftovi (encorafenib). Common drug interactions include pyrexia among females and vomiting among males.

The phase IV clinical study analyzes what interactions people have when they take Oxycontin and Braftovi. It is created by eHealthMe based on reports of 31 people who take the same drugs from the FDA, and is updated regularly.

What is Oxycontin?

Oxycontin has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 212,533 Oxycontin users. Check the latest studies of Oxycontin.

What is Braftovi?

Braftovi has active ingredients of encorafenib. eHealthMe is studying from 7,609 Braftovi users. Check the latest studies of Braftovi.



On Jul, 16, 2026

31 people who take Oxycontin and Braftovi together, and have interactions are studied.

Oxycontin and Braftovi drug interactions.

What are the common drug interactions of Oxycontin and Braftovi, by gender? *:

female:

  1. Pyrexia (fever)
  2. Biliary obstruction
  3. Cholangitis (infection of the bile duct)
  4. Infusion related reaction
  5. Liver abscess (pus in liver)
  6. Decreased appetite
  7. Dehydration (dryness resulting from the removal of water)
  8. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  9. Hepatic encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure)
  10. Neoplasm progression (growth of tumour)

male:

  1. Vomiting
  2. Death
  3. Paronychia (infection in the tissues adjacent to a nail on a finger or toe)
  4. Disease progression
  5. Neoplasm progression (growth of tumour)
  6. Peripheral swelling
  7. Constipation
  8. Dermatitis acneiform (dermatoses including acne vulgaris, rosacea, folliculitis, and perioral dermatitis)
  9. Diarrhoea
  10. Dry skin

What are the common drug interactions of Oxycontin and Braftovi, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Neoplasm progression (growth of tumour)
  2. Peripheral swelling
  3. Vomiting
  4. Death
  5. Disease progression

40-49:

n/a

50-59:

  1. Death

60+:

  1. Pyrexia (fever)
  2. Biliary obstruction
  3. Neoplasm progression (growth of tumour)
  4. Death
  5. Dermatitis acneiform (dermatoses including acne vulgaris, rosacea, folliculitis, and perioral dermatitis)
  6. Diarrhoea
  7. Dry skin
  8. Malaise (a feeling of general discomfort or uneasiness)
  9. Nausea (feeling of having an urge to vomit)
  10. Paronychia (infection in the tissues adjacent to a nail on a finger or toe)

What are the existing conditions these people have? *

  1. Malignant Melanoma (skin cancer rises from melancytes): 7 people, 22.58%
  2. Colon Cancer: 5 people, 16.13%
  3. Neoplasm Malignant (cancer tumour): 4 people, 12.90%
  4. Rectal Cancer (cancer of rectum): 3 people, 9.68%
  5. Cholangiocarcinoma (a cancer that forms glands or secretes significant amounts of mucins): 3 people, 9.68%
  6. Metastatic Malignant Melanoma (spreadable cancer tumour of melanine): 2 people, 6.45%
  7. Constipation: 2 people, 6.45%

* Approximation only. Some reports may have incomplete information.

Do you take Oxycontin and Braftovi?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Oxycontin and Braftovi:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Oxycontin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Braftovi:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Oxycontin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Braftovi and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on oxycodone hydrochloride and encorafenib (the active ingredients of Oxycontin and Braftovi, respectively), and Oxycontin and Braftovi (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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