Oxycontin and Rezulin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Oxycontin (oxycodone hydrochloride) and Rezulin (troglitazone). Common drug interactions include anaemia among females and hepatitis chronic active among males.

The phase IV clinical study analyzes what interactions people have when they take Oxycontin and Rezulin. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Oxycontin?

Oxycontin has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 212,533 Oxycontin users. Check the latest studies of Oxycontin.

What is Rezulin?

Rezulin has active ingredients of troglitazone. eHealthMe is studying from 8,764 Rezulin users. Check the latest studies of Rezulin.

On Aug, 05, 2026

14 people who take Oxycontin and Rezulin together, and have interactions are studied.

Oxycontin and Rezulin drug interactions.

What are the common drug interactions of Oxycontin and Rezulin, by gender? *:

female:

Anaemia (lack of blood)
Application site reaction
Dyspnoea (difficult or laboured respiration)
Haematocrit decreased
Haemoglobin decreased
Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
Oedema (fluid collection in tissue)
Weight increased

male:

Hepatitis chronic active
Hepatomegaly (abnormal enlargement of the liver)
Aortic valve calcification
Aortic valve incompetence
Aortic valve stenosis (narrowing of the aortic valve)
Back disorder
Blood creatinine increased
Dehydration (dryness resulting from the removal of water)
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Ejection fraction decreased (systolic heart failure)

What are the common drug interactions of Oxycontin and Rezulin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Application site reaction

50-59:

Urinary retention (the inability to completely or partially empty the bladder)
Vomiting
Weight decreased
Dehydration (dryness resulting from the removal of water)
Hypotension (abnormally low blood pressure)
Impaired gastric emptying
Injury
Weakness
Acanthosis (thickening of the skin)
Adenocarcinoma (malignant tumour formed from glandular structures in epithelial tissue)

60+:

Hepatitis chronic active
Hepatomegaly (abnormal enlargement of the liver)
Blood bilirubin increased
Blood creatinine increased
Ejection fraction decreased (systolic heart failure)
Hepatitis (inflammation of the liver)
Left ventricular hypertrophy (the thickening of the myocardium (muscle) of the left ventricle of the heart)
Mitral valve incompetence (inefficient heart valve)
Oedema lower limb (fluid collection in tissue of lower leg)
Pericardial effusion (fluid around the heart)

* Approximation only. Some reports may have incomplete information.

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