Oxymetazoline and Omeprazole drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Oxymetazoline (oxymetazoline) and Omeprazole (omeprazole). Common drug interactions include spondylitis among females and pneumonia among males.

The phase IV clinical study analyzes what interactions people have when they take Oxymetazoline and Omeprazole. It is created by eHealthMe based on reports of 28 people who take the same drugs from the FDA, and is updated regularly.

What is Oxymetazoline?

Oxymetazoline has active ingredients of oxymetazoline. eHealthMe is studying from 149 Oxymetazoline users. Check the latest studies of Oxymetazoline.

What is Omeprazole?

Omeprazole has active ingredients of omeprazole. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 410,631 Omeprazole users. Check the latest studies of Omeprazole.



On Jul, 25, 2026

28 people who take Oxymetazoline and Omeprazole together, and have interactions are studied.

Oxymetazoline and Omeprazole drug interactions.

What are the common drug interactions of Oxymetazoline and Omeprazole, by gender? *:

female:

  1. Spondylitis (an inflammation of the vertebra with spinal cord involvement)
  2. Swelling
  3. Temperature regulation disorder (body is unable to maintain temperature)
  4. Tremor (trembling or shaking movements in one or more parts of your body)
  5. Urinary sediment present
  6. Urine leukocyte esterase positive
  7. White blood cell count decreased
  8. Abdominal pain lower
  9. Alopecia (absence of hair from areas of the body)
  10. Cataract (clouding of the lens inside the eye)

male:

  1. Pneumonia
  2. Anal infection
  3. Cluster headache (one-sided head pain with tearing)
  4. Cough
  5. Gastrointestinal disorder (functional problems of gastrointestinal tract)
  6. Headache (pain in head)
  7. Nerve compression
  8. Pneumonia bacterial (pneumonia associated with bacterial infection)
  9. Pneumonia fungal
  10. Prostatitis (inflammation of the prostate gland)

What are the common drug interactions of Oxymetazoline and Omeprazole, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Pain
  2. Weight increased
  3. Diastolic dysfunction
  4. Obstructive sleep apnoea syndrome (frequent pauses in breathing during sleep usually accompanied by loud snoring)

50-59:

  1. Fatigue (feeling of tiredness)
  2. Chronic kidney disease
  3. Death
  4. Renal failure (kidney dysfunction)
  5. Abdominal distension
  6. Blood glucose increased
  7. Gastrointestinal disorder (functional problems of gastrointestinal tract)
  8. Somnolence (a state of near-sleep, a strong desire for sleep)

60+:

  1. Bacterial test positive
  2. Balance disorder
  3. Abdominal discomfort
  4. Abdominal distension
  5. Blood chloride decreased
  6. Blood creatinine increased
  7. Blood iron decreased
  8. Blood sodium decreased
  9. Blood urea increased
  10. Constipation

What are the existing conditions these people have? *

  1. Hereditary Neuropathic Amyloidosis (hereditary- diseases resulting from abnormal deposition of certain proteins (amyloid) in various bodily areas by problems with signals from the nerves): 5 people, 17.86%
  2. Type 2 Diabetes: 4 people, 14.29%
  3. Nausea (feeling of having an urge to vomit): 4 people, 14.29%
  4. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 4 people, 14.29%
  5. Sleep Disorder: 4 people, 14.29%
  6. Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 4 people, 14.29%
  7. Hyperlipidaemia (presence of excess lipids in the blood): 4 people, 14.29%
  8. Neuropathy Peripheral (surface nerve damage): 4 people, 14.29%
  9. Nosebleed (bleeding from nose): 4 people, 14.29%
  10. Rash Maculo-Papular (red area on the skin that is covered with small confluent bumps): 4 people, 14.29%

* Approximation only. Some reports may have incomplete information.

Do you take Oxymetazoline and Omeprazole?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Oxymetazoline and Omeprazole:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Oxymetazoline:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Omeprazole:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Oxymetazoline and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Omeprazole and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on oxymetazoline and omeprazole (the active ingredients of Oxymetazoline and Omeprazole, respectively), and Oxymetazoline and Omeprazole (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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