Ozempic and Belbuca drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ozempic (semaglutide) and Belbuca (buprenorphine hydrochloride). Common drug interactions include productive cough among females and back pain among males.

The phase IV clinical study analyzes what interactions people have when they take Ozempic and Belbuca. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Ozempic?

Ozempic has active ingredients of semaglutide. It is often used in weight loss. eHealthMe is studying from 29,761 Ozempic users. Check the latest studies of Ozempic.

What is Belbuca?

Belbuca has active ingredients of buprenorphine hydrochloride. eHealthMe is studying from 3,022 Belbuca users. Check the latest studies of Belbuca.

On Jul, 19, 2026

13 people who take Ozempic and Belbuca together, and have interactions are studied.

What are the common drug interactions of Ozempic and Belbuca, by gender? *:

female:

Productive cough
Vomiting
Abdominal pain upper
Abdominal tenderness
Arthralgia (joint pain)
Asthenia (weakness)
Back pain
Blood glucose increased
Breast pain
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)

male:

Back pain
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Pain in extremity
Surgery

What are the common drug interactions of Ozempic and Belbuca, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
Oligomenorrhoea (infrequent (or, in occasional usage, very light) menstruation)
Pain in extremity
Headache (pain in head)

40-49:

n/a

50-59:

Chest pain
Confusional state
Death
Diarrhoea
Dyspnoea (difficult or laboured respiration)
Fall
Headache (pain in head)
Hypervolaemia (abnormally increased volume of blood)
Incontinence (lack of moderation or self-control)
Infection

60+:

Dizziness
Ear discomfort
Headache (pain in head)
Presyncope

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 5 people, 38.46%
Rheumatoid Factor: 2 people, 15.38%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 2 people, 15.38%
Cushing's Syndrome (obesity, a rounded face, increased fat): 2 people, 15.38%
Renal Disorder (kidney disease): 1 person, 7.69%
Psoriasis (immune-mediated disease that affects the skin): 1 person, 7.69%
Pain: 1 person, 7.69%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 7.69%
Insulin Resistance: 1 person, 7.69%
Hormone Level Abnormal: 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

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