Ozempic and Midazolam drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ozempic (semaglutide) and Midazolam (midazolam). Common drug interactions include anaphylactic reaction among females and cholecystitis acute among males.

The phase IV clinical study analyzes what interactions people have when they take Ozempic and Midazolam. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Ozempic?

Ozempic has active ingredients of semaglutide. It is often used in weight loss. eHealthMe is studying from 29,761 Ozempic users. Check the latest studies of Ozempic.

What is Midazolam?

Midazolam has active ingredients of midazolam. eHealthMe is studying from 11,246 Midazolam users. Check the latest studies of Midazolam.

On Jul, 17, 2026

19 people who take Ozempic and Midazolam together, and have interactions are studied.

Ozempic and Midazolam drug interactions.

What are the common drug interactions of Ozempic and Midazolam, by gender? *:

female:

Anaphylactic reaction (serious allergic reaction)
Groin infection (infection in groin)
Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)
Sepsis (a severe blood infection that can lead to organ failure and death)
Soft tissue infection
Anal abscess
Anxiety
Depression
Genital abscess (build up of pus in genital)

male:

Cholecystitis acute (rapid infection of gallbladder)
Peripheral ischaemia (impaired circulation to an extremity)
Urinary tract infection
Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream)
Anal abscess
Cellulitis (infection under the skin)
Genital abscess (build up of pus in genital)
Groin abscess (pus in groin)
Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)
Nerve injury

What are the common drug interactions of Ozempic and Midazolam, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Groin infection (infection in groin)
Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)
Sepsis (a severe blood infection that can lead to organ failure and death)
Soft tissue infection
Anal abscess
Anxiety
Depression
Genital abscess (build up of pus in genital)

30-39:

Anal abscess
Cellulitis (infection under the skin)
Genital abscess (build up of pus in genital)
Groin abscess (pus in groin)
Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)
Nerve injury
Pain
Scar
Sepsis (a severe blood infection that can lead to organ failure and death)
Tooth abscess (pus formation in tooth)

40-49:

Anaphylactic reaction (serious allergic reaction)

50-59:

n/a

60+:

Cholecystitis acute (rapid infection of gallbladder)
Peripheral ischaemia (impaired circulation to an extremity)
Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream)
Spinal compression fracture (fracture due to spinal compression on bone)
Sepsis (a severe blood infection that can lead to organ failure and death)
Ischaemic stroke (stroke; caused by an interruption in the flow of blood to the brain)
Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
Biliary sepsis
Blood pressure decreased
Prostate cancer

What are the existing conditions these people have? *

Type 2 Diabetes: 15 people, 78.95%
Diabetes: 13 people, 68.42%
Inflammatory Bowel Disease: 12 people, 63.16%
Neuralgia (pain in one or more nerves): 12 people, 63.16%
Gout (uric acid crystals building up in the body): 12 people, 63.16%
High Blood Pressure: 12 people, 63.16%
Hyperlipidaemia (presence of excess lipids in the blood): 12 people, 63.16%
Ischaemia (insufficient supply of blood to an organ, usually due to a blocked artery): 12 people, 63.16%
Joint Pain: 12 people, 63.16%
Cellulitis (infection under the skin): 12 people, 63.16%

* Approximation only. Some reports may have incomplete information.

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