Ozempic and Morphine sulfate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ozempic (semaglutide) and Morphine sulfate (morphine sulfate). Common drug interactions include oropharyngeal pain among females and nephrolithiasis among males.

The phase IV clinical study analyzes what interactions people have when they take Ozempic and Morphine sulfate. It is created by eHealthMe based on reports of 38 people who take the same drugs from the FDA, and is updated regularly.

What is Ozempic?

Ozempic has active ingredients of semaglutide. It is often used in weight loss. eHealthMe is studying from 29,759 Ozempic users. Check the latest studies of Ozempic.

What is Morphine sulfate?

Morphine sulfate has active ingredients of morphine sulfate. It is often used in pain. eHealthMe is studying from 87,261 Morphine sulfate users. Check the latest studies of Morphine sulfate.

On Jul, 08, 2026

38 people who take Ozempic and Morphine sulfate together, and have interactions are studied.

Ozempic and Morphine sulfate drug interactions.

What are the common drug interactions of Ozempic and Morphine Sulfate, by gender? *:

female:

Oropharyngeal pain
Hypoaesthesia (reduced sense of touch or sensation)
Aphthous ulcer (mouth ulcer)
Lymphadenopathy (disease or enlargement of lymph nodes)
Oral pain
Proctalgia (pain in the rectum)
Vulvovaginal erythema (redness of the skin of vulva and vagina)
Vulvovaginal pain
Arthralgia (joint pain)
Drug ineffective

male:

Nephrolithiasis (calculi in the kidneys)
Blood urine present
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Back injury
Bone density decreased
Bone pain
Chronic kidney disease
Diabetic coma
Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)

What are the common drug interactions of Ozempic and Morphine Sulfate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Bone density decreased
Bone pain
Burning sensation
Chronic kidney disease
Dermatitis atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder)
Drug ineffective
Drug resistance (reduction in effectiveness of a drug)
Emotional distress

50-59:

Blood urine present
Drug hypersensitivity
Henoch-schonlein purpura (inflammation of the blood vessels in the skin and other body organs)
Pruritus (severe itching of the skin)
Renal disorder (kidney disease)
Skin discolouration (change of skin colour)
Ulcer
Vascular rupture
Inflammation
Nausea (feeling of having an urge to vomit)

60+:

Oropharyngeal pain
Aphthous ulcer (mouth ulcer)
Neuropathy peripheral (surface nerve damage)
Pain in extremity
Arthralgia (joint pain)
Constipation
Decreased appetite
Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
Diarrhoea
Ear infection

What are the existing conditions these people have? *

Skin Ulcer: 4 people, 10.53%
Multiple Myeloma (cancer of the plasma cells): 4 people, 10.53%
Wheezing (a high-pitched whistling sound made while you breath): 3 people, 7.89%
Type 2 Diabetes: 3 people, 7.89%
Nausea And Vomiting: 3 people, 7.89%
Nausea (feeling of having an urge to vomit): 3 people, 7.89%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 7.89%
High Blood Cholesterol: 3 people, 7.89%
Dyspnea (difficult or laboured breathing): 3 people, 7.89%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 3 people, 7.89%

* Approximation only. Some reports may have incomplete information.

Do you take Ozempic and Morphine sulfate?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously