Ozempic and Restoril drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ozempic (semaglutide) and Restoril (temazepam). Common drug interactions include foot fracture among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Ozempic and Restoril. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Ozempic?

Ozempic has active ingredients of semaglutide. It is often used in weight loss. eHealthMe is studying from 29,761 Ozempic users. Check the latest studies of Ozempic.

What is Restoril?

Restoril has active ingredients of temazepam. It is often used in insomnia. eHealthMe is studying from 13,522 Restoril users. Check the latest studies of Restoril.

On Jul, 26, 2026

15 people who take Ozempic and Restoril together, and have interactions are studied.

What are the common drug interactions of Ozempic and Restoril, by gender? *:

female:

Foot fracture
Head injury
Infection
Malaise (a feeling of general discomfort or uneasiness)
Pain
Sepsis (a severe blood infection that can lead to organ failure and death)
Skin infection
Abdominal pain
Asthenia (weakness)
Back pain

male:

Chronic kidney disease
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)
Renal impairment (severely reduced kidney function)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
Ischaemia (insufficient supply of blood to an organ, usually due to a blocked artery)

What are the common drug interactions of Ozempic and Restoril, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Abdominal pain
Back pain
Chest discomfort
Dyspnoea (difficult or laboured respiration)
Muscle spasms (muscle contraction)

50-59:

n/a

60+:

Fall
Coronary artery occlusion (complete obstruction of blood flow in a coronary artery)
Asthenia (weakness)
Bowel movement irregularity
Chronic kidney disease
Cough
Discomfort
Erythema (redness of the skin)
Feeling hot
Flushing (the warm, red condition of human skin)

What are the existing conditions these people have? *

Depression: 7 people, 46.67%
Diabetes: 7 people, 46.67%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 5 people, 33.33%
Hypovitaminosis (any of several diseases caused by deficiency of one or more vitamins): 3 people, 20.00%
Pituitary-Dependent Cushing's Syndrome (pituitary dependent hypercortisolism): 3 people, 20.00%
Cushing's Syndrome (obesity, a rounded face, increased fat): 2 people, 13.33%
Diarrhea: 2 people, 13.33%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 13.33%
High Blood Cholesterol: 2 people, 13.33%
High Blood Pressure: 2 people, 13.33%

* Approximation only. Some reports may have incomplete information.

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