Ozempic and Xalatan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ozempic (semaglutide) and Xalatan (latanoprost). Common drug interactions include fatigue among females and abdominal distension among males.

The phase IV clinical study analyzes what interactions people have when they take Ozempic and Xalatan. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Ozempic?

Ozempic has active ingredients of semaglutide. It is often used in weight loss. eHealthMe is studying from 29,761 Ozempic users. Check the latest studies of Ozempic.

What is Xalatan?

Xalatan has active ingredients of latanoprost. It is often used in glaucoma. eHealthMe is studying from 25,550 Xalatan users. Check the latest studies of Xalatan.



On Jul, 14, 2026

13 people who take Ozempic and Xalatan together, and have interactions are studied.

Ozempic and Xalatan drug interactions.

What are the common drug interactions of Ozempic and Xalatan, by gender? *:

female:

  1. Fatigue (feeling of tiredness)
  2. Blood pressure increased
  3. Rash
  4. Urinary tract infection
  5. Blood potassium decreased
  6. Constipation
  7. Decreased activity
  8. Dizziness
  9. Dry skin
  10. Haematocrit decreased

male:

  1. Abdominal distension
  2. Blood glucose increased
  3. Lacrimation increased
  4. Ocular hyperaemia (an abnormally large amount of blood in eye)
  5. Body temperature increased
  6. Drug ineffective
  7. Early satiety (feeling full before completing a normal sized meal)
  8. Flatulence (flatus expelled through the anus)
  9. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  10. Weight decreased

What are the common drug interactions of Ozempic and Xalatan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Abdominal pain
  2. Asthma
  3. Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
  4. Blood potassium decreased
  5. Cardiac failure congestive
  6. Cellulitis (infection under the skin)
  7. Chest discomfort
  8. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  9. Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
  10. Dyspnoea (difficult or laboured respiration)

40-49:

n/a

50-59:

n/a

60+:

  1. Blood pressure increased
  2. Fatigue (feeling of tiredness)
  3. Bowel movement irregularity
  4. Chest pain
  5. Chronic kidney disease
  6. Constipation
  7. Decreased activity
  8. Dizziness
  9. Dry skin
  10. Eye pain

What are the existing conditions these people have? *

  1. High Blood Pressure: 4 people, 30.77%
  2. Ovarian Cancer (cancer of ovary): 4 people, 30.77%
  3. Nausea And Vomiting: 4 people, 30.77%
  4. Nausea (feeling of having an urge to vomit): 4 people, 30.77%
  5. Type 2 Diabetes: 3 people, 23.08%
  6. Asthma: 2 people, 15.38%
  7. Latent Autoimmune Diabetes In Adults (slow progressing diabetes in adult): 2 people, 15.38%
  8. Constipation: 1 person, 7.69%
  9. Cough: 1 person, 7.69%
  10. Cushing's Syndrome (obesity, a rounded face, increased fat): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Ozempic and Xalatan?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Ozempic and Xalatan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ozempic:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Xalatan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ozempic and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Xalatan and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on semaglutide and latanoprost (the active ingredients of Ozempic and Xalatan, respectively), and Ozempic and Xalatan (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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