Pacerone and Remeron drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Pacerone (amiodarone hydrochloride) and Remeron (mirtazapine). Common drug interactions include sepsis among females and thrombocytopenia among males.

The phase IV clinical study analyzes what interactions people have when they take Pacerone and Remeron. It is created by eHealthMe based on reports of 30 people who take the same drugs from the FDA, and is updated regularly.

What is Pacerone?

Pacerone has active ingredients of amiodarone hydrochloride. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 2,814 Pacerone users. Check the latest studies of Pacerone.

What is Remeron?

Remeron has active ingredients of mirtazapine. It is often used in depression. eHealthMe is studying from 26,474 Remeron users. Check the latest studies of Remeron.



On Jul, 21, 2026

30 people who take Pacerone and Remeron together, and have interactions are studied.

Pacerone and Remeron drug interactions.

What are the common drug interactions of Pacerone and Remeron, by gender? *:

female:

  1. Sepsis (a severe blood infection that can lead to organ failure and death)
  2. Wheezing (a high-pitched whistling sound made while you breath)
  3. Renal failure (kidney dysfunction)
  4. Arthralgia (joint pain)
  5. Carotid artery stenosis (narrowing of carotid artery)
  6. Carotid bruit (sound heard over the carotid artery area during auscultation)
  7. Chest discomfort
  8. Decreased appetite
  9. Emotional disorder
  10. Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)

male:

  1. Thrombocytopenia (decrease of platelets in blood)
  2. Asthenia (weakness)
  3. Failure to thrive (inadequate weight gain and physical growth in children)
  4. Hip fracture
  5. Hyperkalaemia (damage to or disease of the kidney)
  6. Hypertension (high blood pressure)
  7. Metastases to lung (cancer spreads to lung)
  8. Oedema peripheral (superficial swelling)
  9. Pulmonary embolism (blockage of the main artery of the lung)
  10. Tremor (trembling or shaking movements in one or more parts of your body)

What are the common drug interactions of Pacerone and Remeron, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Atelectasis (partial or complete collapse of the lung)
  2. Blood potassium decreased
  3. Cardiac failure congestive
  4. Cardioactive drug level decreased
  5. Cardiomegaly (increased size of heart than normal)
  6. Cardiomyopathy (weakening of the heart muscle)
  7. Chest discomfort
  8. Chest pain
  9. Congestive cardiomyopathy (weakening of heart muscle)
  10. Dehydration (dryness resulting from the removal of water)

40-49:

n/a

50-59:

  1. Fall
  2. Acute respiratory distress syndrome
  3. Cardiac autonomic neuropathy (malfunction of nervous system for heart due to diabetes)
  4. Cardiac disorder
  5. Cardiac failure
  6. Cardiogenic shock (inadequate circulation of blood)
  7. Dyspnoea (difficult or laboured respiration)
  8. Malaise (a feeling of general discomfort or uneasiness)
  9. Pulmonary hypertension (increase in blood pressure in the lung artery)
  10. Respiratory failure (inadequate gas exchange by the respiratory system)

60+:

  1. Dehydration (dryness resulting from the removal of water)
  2. Pain
  3. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  4. Respiratory distress (difficulty in breathing)
  5. Weight decreased
  6. Asthenia (weakness)
  7. Blood pressure increased
  8. Decreased appetite
  9. Emotional disorder
  10. Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)

What are the existing conditions these people have? *

  1. High Blood Pressure: 4 people, 13.33%
  2. Pain: 4 people, 13.33%
  3. Dementia Alzheimer's Type (loss of mental ability with alzheimer's symptom): 4 people, 13.33%
  4. Arrhythmias (irregular heartbeat): 3 people, 10.00%
  5. Cardiac Disorder: 3 people, 10.00%
  6. Cardiac Failure Congestive: 3 people, 10.00%
  7. Nausea And Vomiting: 3 people, 10.00%
  8. Nausea (feeling of having an urge to vomit): 3 people, 10.00%
  9. Multiple Myeloma (cancer of the plasma cells): 3 people, 10.00%
  10. Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 3 people, 10.00%

* Approximation only. Some reports may have incomplete information.

Do you take Pacerone and Remeron?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Pacerone and Remeron:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Pacerone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Remeron:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Pacerone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Remeron and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on amiodarone hydrochloride and mirtazapine (the active ingredients of Pacerone and Remeron, respectively), and Pacerone and Remeron (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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