Palbociclib and Apixaban drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Palbociclib (palbociclib) and Apixaban (apixaban). Common drug interactions include rash pruritic among females and anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Palbociclib and Apixaban. It is created by eHealthMe based on reports of 57 people who take the same drugs from the FDA, and is updated regularly.

What is Palbociclib?

Palbociclib has active ingredients of palbociclib. eHealthMe is studying from 11,622 Palbociclib users. Check the latest studies of Palbociclib.

What is Apixaban?

Apixaban has active ingredients of apixaban. It is often used in blood clots. eHealthMe is studying from 60,351 Apixaban users. Check the latest studies of Apixaban.



On Jul, 09, 2026

57 people who take Palbociclib and Apixaban together, and have interactions are studied.

Palbociclib and Apixaban drug interactions.

What are the common drug interactions of Palbociclib and Apixaban, by gender? *:

female:

  1. Rash pruritic (redness with itching)
  2. Tumour marker increased
  3. Metastases to bone (cancer spreads to bone)
  4. Weight decreased
  5. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  6. Depression
  7. Fall
  8. Pleural effusion (water on the lungs)
  9. Malignant neoplasm progression (cancer tumour came back)
  10. Abdominal pain upper

male:

  1. Anaemia (lack of blood)
  2. Pericardial effusion (fluid around the heart)

What are the common drug interactions of Palbociclib and Apixaban, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Glaucoma (increased fluid pressure in the eye with vision loss)
  2. Osteonecrosis of jaw (death of bone of jaw)
  3. Cancer pain
  4. Cataract (clouding of the lens inside the eye)
  5. Depression
  6. Fall
  7. Polyneuropathy (neurological disorder that occurs when many peripheral nerves throughout the body malfunction simultaneously)

50-59:

n/a

60+:

  1. Fatigue (feeling of tiredness)
  2. Back pain
  3. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  4. Malignant neoplasm progression (cancer tumour came back)
  5. Metastases to bone (cancer spreads to bone)
  6. Weight decreased
  7. Asthenia (weakness)
  8. Embolism (obstruction of an artery, typically by a clot of blood or an air bubble)
  9. General physical health deterioration (weak health status)
  10. Haemoglobin decreased

What are the existing conditions these people have? *

  1. Breast Cancer: 25 people, 43.86%
  2. Breast Cancer Metastatic: 21 people, 36.84%
  3. High Blood Pressure: 14 people, 24.56%
  4. Metastases To Bone (cancer spreads to bone): 13 people, 22.81%
  5. Dyslipidaemia (abnormal amount of lipids): 10 people, 17.54%
  6. Oedema (fluid collection in tissue): 9 people, 15.79%
  7. Heart Attack: 8 people, 14.04%
  8. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 7 people, 12.28%
  9. Pain: 5 people, 8.77%
  10. Constipation: 5 people, 8.77%

* Approximation only. Some reports may have incomplete information.

Do you take Palbociclib and Apixaban?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Palbociclib and Apixaban:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Palbociclib:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Apixaban:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Palbociclib and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Apixaban and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on palbociclib and apixaban (the active ingredients of Palbociclib and Apixaban, respectively), and Palbociclib and Apixaban (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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