Palbociclib and Valtrex drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Palbociclib (palbociclib) and Valtrex (valacyclovir hydrochloride). Common drug interactions include thrombocytopenia among females and abdominal pain among males.

The phase IV clinical study analyzes what interactions people have when they take Palbociclib and Valtrex. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Palbociclib?

Palbociclib has active ingredients of palbociclib. eHealthMe is studying from 11,622 Palbociclib users. Check the latest studies of Palbociclib.

What is Valtrex?

Valtrex has active ingredients of valacyclovir hydrochloride. It is often used in genital herpes. eHealthMe is studying from 39,999 Valtrex users. Check the latest studies of Valtrex.

On Jul, 24, 2026

16 people who take Palbociclib and Valtrex together, and have interactions are studied.

Palbociclib and Valtrex drug interactions.

What are the common drug interactions of Palbociclib and Valtrex, by gender? *:

female:

Thrombocytopenia (decrease of platelets in blood)
Hypersensitivity
Cough
Embolism (obstruction of an artery, typically by a clot of blood or an air bubble)
Oxygen saturation decreased
Blood creatinine increased
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
Pulmonary oedema (fluid accumulation in the lungs)
Sepsis (a severe blood infection that can lead to organ failure and death)
Abdominal pain

male:

Abdominal pain
Cholecystitis acute (rapid infection of gallbladder)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Unresponsive to stimuli
Back pain
Cold sweat
Hypoxia (low oxygen in tissues)
Lethargy (tiredness)
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Pyrexia (fever)

What are the common drug interactions of Palbociclib and Valtrex, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Cough
Oxygen saturation decreased
Thrombocytopenia (decrease of platelets in blood)
Bronchial obstruction (blockage of the breathing passages to the lungs)
Chest pain
Fibrosis (formation of excess fibrous connective tissue in an organ or tissue)
Granuloma (a small area of inflammation due to tissue injury)
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Headache (pain in head)
Hilar lymphadenopathy (disease of the lymph nodes due to infection)

40-49:

Hypersensitivity

50-59:

Blood creatinine increased
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
Sepsis (a severe blood infection that can lead to organ failure and death)
Thrombocytopenia (decrease of platelets in blood)

60+:

Abdominal pain
Embolism (obstruction of an artery, typically by a clot of blood or an air bubble)
Pyrexia (fever)
Somnolence (a state of near-sleep, a strong desire for sleep)
Supraventricular extrasystoles (premature electrical impulse in the heart, generated above the level of the ventricle)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Unresponsive to stimuli
Cholecystitis acute (rapid infection of gallbladder)
Pulmonary oedema (fluid accumulation in the lungs)
Back pain

What are the existing conditions these people have? *

Breast Cancer Metastatic: 11 people, 68.75%
Pain: 7 people, 43.75%
Headache (pain in head): 6 people, 37.50%
Nausea (feeling of having an urge to vomit): 6 people, 37.50%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 31.25%
Muscle Aches (muscle pain): 5 people, 31.25%
Insomnia (sleeplessness): 5 people, 31.25%
Joint Pain: 5 people, 31.25%
Stomatitis (inflammation of mucous membrane of mouth): 5 people, 31.25%
Asthma: 4 people, 25.00%

* Approximation only. Some reports may have incomplete information.

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