Pamelor and Ditropan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Pamelor (nortriptyline hydrochloride) and Ditropan (oxybutynin chloride). Common drug interactions include diabetes mellitus inadequate control among females and dizziness among males.

The phase IV clinical study analyzes what interactions people have when they take Pamelor and Ditropan. It is created by eHealthMe based on reports of 54 people who take the same drugs from the FDA, and is updated regularly.

What is Pamelor?

Pamelor has active ingredients of nortriptyline hydrochloride. It is often used in migraine. eHealthMe is studying from 4,069 Pamelor users. Check the latest studies of Pamelor.

What is Ditropan?

Ditropan has active ingredients of oxybutynin chloride. It is often used in urge incontinence. eHealthMe is studying from 11,799 Ditropan users. Check the latest studies of Ditropan.

On Jul, 10, 2026

54 people who take Pamelor and Ditropan together, and have interactions are studied.

What are the common drug interactions of Pamelor and Ditropan, by gender? *:

female:

Diabetes mellitus inadequate control
Dna antibody positive
Dry skin
Ear disorder
Ear infection
Enterobacter test positive
Enterococcus test positive
Exercise tolerance decreased
Frustration (a form of poorly expressed anger)
Gastrointestinal viral infection (virus infection of gastrointestinal tract)

male:

Dizziness
Gallbladder operation
Benign mesothelioma (non-cancerous tumour)
Central nervous system lesion (an abnormality in tissue of brain or spinal cord)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Cholecystitis (infection of gallbladder)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Chronic kidney disease
Colonic polyp (extra part of colon tissue grow in intestine)
Constipation

What are the common drug interactions of Pamelor and Ditropan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Central nervous system lesion (an abnormality in tissue of brain or spinal cord)
Urinary tract infection

30-39:

Chronic kidney disease
Renal failure (kidney dysfunction)

40-49:

Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Drug hypersensitivity
Fatigue (feeling of tiredness)
Urinary tract infection
Adverse drug reaction
Anaemia (lack of blood)
Application site reaction
Body temperature increased
Burning sensation
Cellulitis staphylococcal (a type of bacteria originated skin soft tissue infection)

50-59:

Implant site scar
Initial insomnia (feeling of inadequate or poor-quality sleep)
Injection site abscess
Injury
Loss of control of legs
Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Muscle spasms (muscle contraction)
Muscle spasticity (tight or stiff muscles and an inability to control those muscles)
Muscle tightness
Myalgia (muscle pain)

60+:

Dizziness
Drug ineffective
Neurogenic bladder (the normal function of the bladder is to store and empty urine in a coordinated, controlled fashion)
Renal impairment (severely reduced kidney function)
Sudden death
Throat irritation
Weakness
Breast cancer female
Burning sensation
Cardiac disorder

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 15 people, 27.78%
Gastrointestinal Disorder (functional problems of gastrointestinal tract): 6 people, 11.11%
Headache (pain in head): 6 people, 11.11%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 6 people, 11.11%
Fatigue (feeling of tiredness): 5 people, 9.26%
High Blood Pressure: 5 people, 9.26%
Diabetes: 5 people, 9.26%
Diabetic Neuropathy (neuropathic disorders that are associated with diabetes mellitus): 4 people, 7.41%
Dementia (madness): 4 people, 7.41%
Constipation: 4 people, 7.41%

* Approximation only. Some reports may have incomplete information.

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