Pamelor and Sucralfate drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Pamelor (nortriptyline hydrochloride) and Sucralfate (sucralfate). Common drug interactions include maternal exposure during pregnancy among females and chronic kidney disease among males.
The phase IV clinical study analyzes what interactions people have when they take Pamelor and Sucralfate. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.
What is Pamelor?
Pamelor has active ingredients of nortriptyline hydrochloride. It is often used in migraine. eHealthMe is studying from 4,069 Pamelor users. Check the latest studies of Pamelor.
What is Sucralfate?
Sucralfate has active ingredients of sucralfate. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 17,548 Sucralfate users. Check the latest studies of Sucralfate.
18 people who take Pamelor and Sucralfate together, and have interactions are studied.

What are the common drug interactions of Pamelor and Sucralfate, by gender? *:
female:
- Maternal exposure during pregnancy (use of substance during pregnancy)
- Iron deficiency anaemia
- Premature delivery
- Impaired gastric emptying
- Intervertebral disc degeneration (spinal disc degeneration)
- Irritable bowel syndrome
- Renal failure (kidney dysfunction)
- Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
- Hypersensitivity
- Pancreatitis chronic (chronic inflammation of pancreas)
male:
- Chronic kidney disease
- Renal failure (kidney dysfunction)
- Upper gastrointestinal haemorrhage (upper gastrointestinal bleeding)
- Abdominal pain
- Bladder cancer
- Drug hypersensitivity
- Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
- Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
- Premature baby
- Nephrogenic anaemia (anaemia due to kidney disease)
What are the common drug interactions of Pamelor and Sucralfate, by age (0-1 to 60+)? *:
0-1:
- Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
- Premature baby
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Upper gastrointestinal haemorrhage (upper gastrointestinal bleeding)
40-49:
- Chronic kidney disease
- Premature delivery
- Renal failure (kidney dysfunction)
- Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
- Abdominal pain
- Bladder cancer
- Drug hypersensitivity
- Pre-eclampsia (high blood pressure and significant amounts of protein in the urine of a pregnant woman)
- Renal hypertension (high blood pressure caused by the kidneys hormonal response)
- Renal tubular necrosis (death of kidney tubules)
50-59:
- Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
- Hypersensitivity
- Impaired gastric emptying
- Intervertebral disc degeneration (spinal disc degeneration)
- Irritable bowel syndrome
- Pancreatitis chronic (chronic inflammation of pancreas)
- Thyroid disorder (thyroid diseases)
60+:
- Renal failure (kidney dysfunction)
- Chronic kidney disease
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Bruxism (habitual grinding of the teeth, typically during sleep)
- Burning sensation
- Butterfly rash
- Cataract (clouding of the lens inside the eye)
- Choking (mechanical obstruction of the flow of air from the environment into the lungs)
- Chorea (abnormal involuntary movement disorder)
- Colonic polyp (extra part of colon tissue grow in intestine)
What are the existing conditions these people have? *
- Pain: 14 people, 77.78%
- Depression: 11 people, 61.11%
- High Blood Pressure: 9 people, 50.00%
- Stress And Anxiety: 8 people, 44.44%
- Rickets (softening of bones): 7 people, 38.89%
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 7 people, 38.89%
- Diabetes: 7 people, 38.89%
- Intestinal Obstruction: 7 people, 38.89%
- High Blood Cholesterol: 5 people, 27.78%
- Dizziness: 4 people, 22.22%
* Approximation only. Some reports may have incomplete information.
Do you take Pamelor and Sucralfate?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Pamelor (4,069 reports)
- Sucralfate (17,548 reports)
Browse all drug interactions of Pamelor and Sucralfate:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Pamelor:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Sucralfate:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Pamelor and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Sucralfate and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on nortriptyline hydrochloride and sucralfate (the active ingredients of Pamelor and Sucralfate, respectively), and Pamelor and Sucralfate (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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