Pancuronium and Methylprednisolone drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Pancuronium (pancuronium bromide) and Methylprednisolone (methylprednisolone). Common drug interactions include injury among females and rhabdomyolysis among males.
The phase IV clinical study analyzes what interactions people have when they take Pancuronium and Methylprednisolone. It is created by eHealthMe based on reports of 44 people who take the same drugs from the FDA, and is updated regularly.
What is Pancuronium?
Pancuronium has active ingredients of pancuronium bromide. eHealthMe is studying from 1,328 Pancuronium users. Check the latest studies of Pancuronium.
What is Methylprednisolone?
Methylprednisolone has active ingredients of methylprednisolone. It is often used in inflammation. eHealthMe is studying from 59,645 Methylprednisolone users. Check the latest studies of Methylprednisolone.
44 people who take Pancuronium and Methylprednisolone together, and have interactions are studied.

What are the common drug interactions of Pancuronium and Methylprednisolone, by gender? *:
female:
- Injury
- Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
- Pain
- Psychiatric symptom
- Renal failure (kidney dysfunction)
- Renal impairment (severely reduced kidney function)
- Renal injury (kidney injury)
- Stress
- Base excess increased
- Blood albumin decreased
male:
- Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
- Renal failure acute (rapid kidney dysfunction)
- Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
- Blood urea increased
- Cardiac arrest
- Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
- Hypotension (abnormally low blood pressure)
- Obstructive airways disorder (a progressive disease that makes it hard to breathe)
- Po2 decreased
- Respiratory failure (inadequate gas exchange by the respiratory system)
What are the common drug interactions of Pancuronium and Methylprednisolone, by age (0-1 to 60+)? *:
0-1:
- Ascites (accumulation of fluid in the abdominal cavity)
- Abdominal abscess (collection of pus in abdomen)
- Acute circulatory failure (shock)
- Angioneurotic oedema (swelling that occurs just beneath the surface of the skin or mucous membranes)
- Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
- Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
- Hyperpyrexia malignant (disease passed down through families that causes a fast rise in body temperature (fever) and severe muscle contractions- infectious)
- Hypovitaminosis (any of several diseases caused by deficiency of one or more vitamins)
- Mucosal haemorrhage (bleeding from mucous membrane)
- Oedema (fluid collection in tissue)
2-9:
- Ascites (accumulation of fluid in the abdominal cavity)
- Angioedema (rapid swelling of the dermis)
- Obstructive airways disorder (a progressive disease that makes it hard to breathe)
- Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
- Angioneurotic oedema (swelling that occurs just beneath the surface of the skin or mucous membranes)
- Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
- Blood pressure decreased
- Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
- Haemorrhage (bleeding)
- Mucosal inflammation (infection of mucous membrane)
10-19:
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Death
- Depression
- Fear
- Injury
- Pain
- Renal failure (kidney dysfunction)
20-29:
- Propofol infusion syndrome
- Renal failure acute (rapid kidney dysfunction)
- Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
- Anuria (failure of the kidneys to produce urine)
- Neuromyopathy (disease of both muscles and nerves)
- Oliguria (not enough urine)
30-39:
- Aortic valve disease
- Cardiac failure congestive
- Cardiac valve disease (heart valve disease)
- Cerebral artery embolism (sudden blocking of an artery by a clot or foreign material)
- Cerebral infarction (less blood supply to brain resulting tissue damage)
- Coma (state of unconsciousness lasting more than six hours)
- Kidney transplant rejection
- Leukaemoid reaction (elevated white blood cell count, or leukocytosis, that is a physiological response to stress or infection)
- Post procedural complication
- Pseudobulbar palsy (inability to control facial movements (such as chewing and speaking))
40-49:
- Acute pulmonary oedema (sudden deposit of fluid in the lung))
- Acute respiratory distress syndrome
- Blood pressure decreased
- Oedema (fluid collection in tissue)
- Pyelonephritis (inflammation of kidney caused by bacteria)
- Weight increased
- Ascites (accumulation of fluid in the abdominal cavity)
- Blood lactic acid increased
- Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
- Disease recurrence
50-59:
- Anaphylactic reaction (serious allergic reaction)
- Blood creatine phosphokinase increased
- Blood creatine phosphokinase mb increased
- Blood creatinine increased
- Cardiac arrest
- Disseminated intravascular coagulation (systemic activation of blood coagulation)
- Hyperkalaemia (damage to or disease of the kidney)
- Hypotension (abnormally low blood pressure)
- Multi-organ failure (multisystem organ failure)
- Myoglobinuria present (presence of myoglobin in the urine)
60+:
- Po2 decreased
- Respiratory failure (inadequate gas exchange by the respiratory system)
- Blood urea increased
- Bradycardia (abnormally slow heart action)
- Cardiac arrest
- Cardiac failure
- Cerebral atrophy (decrement in size of brain)
- Coronary artery stenosis (narrowing of coronary artery)
- Depressed level of consciousness
- Gastritis erosive (a break in the surface layer of the membrane lining the stomach with infection)
What are the existing conditions these people have? *
- Sedation: 7 people, 15.91%
- Nausea (feeling of having an urge to vomit): 3 people, 6.82%
- Immunodeficiency Disorders: 3 people, 6.82%
- Aspergillosis (an infection caused by a fungus called aspergillus): 3 people, 6.82%
* Approximation only. Some reports may have incomplete information.
Do you take Pancuronium and Methylprednisolone?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Pancuronium (1,328 reports)
- Methylprednisolone (59,645 reports)
Browse all drug interactions of Pancuronium and Methylprednisolone:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Pancuronium:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Methylprednisolone:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Pancuronium and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Methylprednisolone and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on pancuronium bromide and methylprednisolone (the active ingredients of Pancuronium and Methylprednisolone, respectively), and Pancuronium and Methylprednisolone (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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