Pantoprazole sodium and Nucynta drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Pantoprazole sodium (pantoprazole sodium) and Nucynta (tapentadol hydrochloride). Common drug interactions include neck pain among females and weight decreased among males.

The phase IV clinical study analyzes what interactions people have when they take Pantoprazole sodium and Nucynta. It is created by eHealthMe based on reports of 89 people who take the same drugs from the FDA, and is updated regularly.

What is Pantoprazole sodium?

Pantoprazole sodium has active ingredients of pantoprazole sodium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 66,891 Pantoprazole sodium users. Check the latest studies of Pantoprazole sodium.

What is Nucynta?

Nucynta has active ingredients of tapentadol hydrochloride. It is often used in pain. eHealthMe is studying from 31,818 Nucynta users. Check the latest studies of Nucynta.

On Jul, 12, 2026

89 people who take Pantoprazole sodium and Nucynta together, and have interactions are studied.

Pantoprazole sodium and Nucynta drug interactions.

What are the common drug interactions of Pantoprazole Sodium and Nucynta, by gender? *:

female:

Neck pain
Nephrolithiasis (calculi in the kidneys)
Neuropathy peripheral (surface nerve damage)
Peripheral swelling
Pyrexia (fever)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Sinusitis (inflammation of sinus)
Sjogren's syndrome (a disease that causes dryness in the mouth and eyes)
Therapeutic response unexpected
Ulnar neuritis (inflammation or compression of the ulnar nerve)

male:

Weight decreased
Chronic kidney disease
Anxiety
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Decreased appetite
Depression
Diarrhoea
Fall

What are the common drug interactions of Pantoprazole Sodium and Nucynta, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Hypertension (high blood pressure)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)

30-39:

Hospitalisation
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)

40-49:

Fatigue (feeling of tiredness)
Headache (pain in head)
Nausea (feeling of having an urge to vomit)
Abdominal discomfort
Aggression
Agitation (state of anxiety or nervous excitement)
Anxiety
Asthenia (weakness)
Impaired gastric emptying
Restless legs syndrome (a powerful urge to move your legs)

50-59:

Swelling
Urinary tract infection
Viral load increased
Vomiting
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Asthenia (weakness)
Bedridden
Colostomy
Drug ineffective
Feeling hot

60+:

Urinary tract infection
Fluid retention (an abnormal accumulation of fluid in the blood)
Arthropathy
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Blood pressure increased
Blood pressure systolic increased
C-reactive protein increased
Cardiac failure congestive
Contusion (a type of hematoma of tissue in which capillaries)
Cough

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 44 people, 49.44%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 29 people, 32.58%
Immunodeficiency Common Variable: 8 people, 8.99%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 6 people, 6.74%
Multiple Myeloma (cancer of the plasma cells): 5 people, 5.62%
Drowsiness: 5 people, 5.62%

* Approximation only. Some reports may have incomplete information.

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